AANAT Produits
(Aralkylamine N-Acetyltransferase (AANAT))
Catégories
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Catégories AANAT en vedette
AANAT Anticorps
High quality antibodies with extensive validation data.
AANAT Kits ELISA
Reliable ELISA kits for a wide range of species.
AANAT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
AANAT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat, Sheep
Application
ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (2)
- (6)
N° du produit
ABIN751063
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, ICC, IP
Validations
- (2)
N° du produit
ABIN7444538
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (2)
N° du produit
ABIN7169324
Quantité
100 μg
Fiche technique
Fiche technique
AANAT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965002
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965001
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953911
Quantité
96 tests
Fiche technique
Fiche technique
AANAT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305403
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7395332
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7418458
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits AANAT
: "Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism." dans: Reproductive biology and endocrinology : RB&E, Vol. 17, Issue 1, pp. 1, (2019) (PubMed).: "Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord." dans: Journal of veterinary science, Vol. 15, Issue 3, pp. 335-42, (2016) (PubMed).
: "Arylalkylamine N-acetyltransferase: "the Timezyme"." dans: The Journal of biological chemistry, Vol. 282, Issue 7, pp. 4233-7, (2007) (PubMed).
: "14-3-3 proteins in pineal photoneuroendocrine transduction: how many roles?" dans: Journal of neuroendocrinology, Vol. 15, Issue 4, pp. 370-7, (2003) (PubMed).
: "Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase." dans: Investigative ophthalmology & visual science, Vol. 43, Issue 2, pp. 564-72, (2002) (PubMed).
: "14-3-3 Proteins and photoneuroendocrine transduction: role in controlling the daily rhythm in melatonin." dans: Biochemical Society transactions, Vol. 30, Issue 4, pp. 365-73, (2002) (PubMed).
: "Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87)." dans: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 10, pp. 4699-706, (2002) (PubMed).
: "cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation." dans: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24097-107, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à AANAT
aralkylamine N-acetyltransferase (AANAT), aralkylamine N-acetyltransferase (Aanat), arylalkylamine N-acetyltransferase (Aanat), AA-NAT, DSPS, Nat-2, Nat4, SNAT, SnatProtein level used designations for AANAT
- arylalkylamine N-acetyltransferase
- serotonin N-acetyltransferase
- serotonin acetylase
- Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase)
- Seretonin N-acetyltransferase
- arylakylamine N-acetyltransferase
- AA-NAT
- pineal serotonin N-acetyltransferase
- pineal arylalkylamine N-acetyltransferase
- aralkylamine N-acetyltransferase
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