ABCA1 Produits
(ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
Catégories
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008].
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Catégories ABCA1 en vedette
ABCA1 Anticorps
High quality antibodies with extensive validation data.
ABCA1 Kits ELISA
Reliable ELISA kits for a wide range of species.
ABCA1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ABCA1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7433312
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7433309
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, IHC (p)
Validations
- (2)
N° du produit
ABIN1099759
Quantité
50 μL
Fiche technique
Fiche technique
ABCA1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6953966
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965059
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965058
Quantité
96 tests
Fiche technique
Fiche technique
ABCA1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305421
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7393556
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7424299
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ABCA1
: "Macrophage iron retention aggravates atherosclerosis: Evidence for the role of autocrine formation of hepcidin in plaque macrophages." dans: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1865, Issue 2, pp. 158531, (2020) (PubMed).: "Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression." dans: Journal of pharmacological sciences, Vol. 142, Issue 1, pp. 9-15, (2020) (PubMed).
: "Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress." dans: Cancer research, Vol. 80, Issue 2, pp. 189-203, (2020) (PubMed).
: "Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages." dans: Frontiers in immunology, Vol. 9, pp. 135, (2019) (PubMed).
: "Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux." dans: Oncogene, Vol. 38, Issue 12, pp. 2135-2150, (2019) (PubMed).
: "OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice." dans: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 1, pp. 161-180, (2019) (PubMed).
: "Nutritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages." dans: Molecular nutrition & food research, Vol. 63, Issue 2, pp. e1800713, (2019) (PubMed).
: "Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages." dans: Molecular and cellular biology, Vol. 39, Issue 5, (2019) (PubMed).
: "Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages." dans: Journal of lipid research, Vol. 60, Issue 3, pp. 506-515, (2019) (PubMed).
: "E3317 promotes cholesterol efflux in macrophage cells via enhancing ABCA1 expression." dans: Biochemical and biophysical research communications, Vol. 504, Issue 1, pp. 68-74, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à ABCA1
ATP binding cassette subfamily A member 1 (ABCA1), ATP binding cassette subfamily A member 1 (Abca1), ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1), ATP binding cassette subfamily A member 1 (abca1), ATP-binding cassette, sub-family A (ABC1), member 1 (Abca1), ATP-binding cassette A1 (ABCA1), ATP-binding cassette, sub-family A (ABC1), member 1B (abca1b), ABC-1, ABC1, Abc1, ABCA1, Arabidopsis thaliana ATP-binding cassette A1, AtABCA1, ATP-binding cassette A1, CERP, HDLDT1, im:7136239, sb:cb407, TGD, wu:fa07e06, zgc:171581Protein level used designations for ABCA1
- ATP-binding cassette sub-family A member 1
- ATP-binding cassette transporter A1
- cholesterol efflux regulatory protein
- membrane-bound
- ATP-binding cassette, sub-family A (ABC1), member 1
- ATP-binding cassette, sub-family A member 1
- ATP-binding cassette transporter 1
- Cholesterol efflux regulatory protein
- ATP-binding cassette transporter
- ATP-binding cassette, sub-family A member 1-like
- ATP-binding cassette sub-family A member 1-like
- ATP-binding cassette 1
- ATP-binding cassette, sub-family A (ABC1), member 1B
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