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ABCA1 Produits

(ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008].

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Catégories ABCA1 en vedette

ABCA1 Anticorps

High quality antibodies with extensive validation data.

ABCA1 Kits ELISA

Reliable ELISA kits for a wide range of species.

ABCA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ABCA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7433312
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7433309
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC, IHC (p)
Validations
  • (2)
N° du produit ABIN1099759
Quantité 50 μL
Fiche technique Fiche technique

ABCA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6953966
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965059
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965058
Quantité 96 tests
Fiche technique Fiche technique

ABCA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305421
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7393556
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7424299
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ABCA1

Xiao, Luo, Guo, Jiang, Zeng, Zhou, Li, Yu, Yao: "Macrophage iron retention aggravates atherosclerosis: Evidence for the role of autocrine formation of hepcidin in plaque macrophages." dans: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1865, Issue 2, pp. 158531, (2020) (PubMed).

Koga, Kanaoka, Okamoto, Nakao, Inada, Takayama, Kataoka, Yamauchi: "Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression." dans: Journal of pharmacological sciences, Vol. 142, Issue 1, pp. 9-15, (2020) (PubMed).

Kaymak, Maier, Schmitz, Campbell, Dankworth, Ade, Walz, Paauwe, Kalogirou, Marouf, Rosenfeldt, Gay, McGregor, Sansom, Schulze: "Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress." dans: Cancer research, Vol. 80, Issue 2, pp. 189-203, (2020) (PubMed).

Han, Zhuang, Shumyak, Wu, Xie, Li, Yang, Reeves: "Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages." dans: Frontiers in immunology, Vol. 9, pp. 135, (2019) (PubMed).

Torres-Adorno, Vitrac, Qi, Tan, Levental, Fan, Yang, Chapkin, Eckhardt, Ueno: "Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux." dans: Oncogene, Vol. 38, Issue 12, pp. 2135-2150, (2019) (PubMed).

Yuan, Guo, Zhou, Du, Jiang, Zhou, Liu, Chi, Ji, Gao, Chen, Lang, Xu, Liu, Yang, Qiu, Tang, Chen, Zou: "OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice." dans: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 1, pp. 161-180, (2019) (PubMed).

OReilly, Kajani, Ralston, Lenighan, Roche, McGillicuddy: "Nutritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages." dans: Molecular nutrition & food research, Vol. 63, Issue 2, pp. e1800713, (2019) (PubMed).

Ramón-Vázquez, de la Rosa, Tabraue, Lopez, Díaz-Chico, Bosca, Tontonoz, Alemany, Castrillo: "Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages." dans: Molecular and cellular biology, Vol. 39, Issue 5, (2019) (PubMed).

Vaidya, Jentsch, Peters, Keul, Weske, Gräler, Mladenov, Iliakis, Heusch, Levkau: "Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages." dans: Journal of lipid research, Vol. 60, Issue 3, pp. 506-515, (2019) (PubMed).

Wang, Luo, Li, Liu, Han, Liu, Zuo, Jiang, Li, Xu, Si: "E3317 promotes cholesterol efflux in macrophage cells via enhancing ABCA1 expression." dans: Biochemical and biophysical research communications, Vol. 504, Issue 1, pp. 68-74, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à ABCA1

ATP binding cassette subfamily A member 1 (ABCA1), ATP binding cassette subfamily A member 1 (Abca1), ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1), ATP binding cassette subfamily A member 1 (abca1), ATP-binding cassette, sub-family A (ABC1), member 1 (Abca1), ATP-binding cassette A1 (ABCA1), ATP-binding cassette, sub-family A (ABC1), member 1B (abca1b), ABC-1, ABC1, Abc1, ABCA1, Arabidopsis thaliana ATP-binding cassette A1, AtABCA1, ATP-binding cassette A1, CERP, HDLDT1, im:7136239, sb:cb407, TGD, wu:fa07e06, zgc:171581

Protein level used designations for ABCA1

  • ATP-binding cassette sub-family A member 1
  • ATP-binding cassette transporter A1
  • cholesterol efflux regulatory protein
  • membrane-bound
  • ATP-binding cassette, sub-family A (ABC1), member 1
  • ATP-binding cassette, sub-family A member 1
  • ATP-binding cassette transporter 1
  • Cholesterol efflux regulatory protein
  • ATP-binding cassette transporter
  • ATP-binding cassette, sub-family A member 1-like
  • ATP-binding cassette sub-family A member 1-like
  • ATP-binding cassette 1
  • ATP-binding cassette, sub-family A (ABC1), member 1B
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