ABCC2 Produits
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))
Catégories
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine\; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008].
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Catégories ABCC2 en vedette
ABCC2 Anticorps
High quality antibodies with extensive validation data.
ABCC2 Kits ELISA
Reliable ELISA kits for a wide range of species.
ABCC2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ABCC2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7441076
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (3)
N° du produit
ABIN737541
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
N° du produit
ABIN514490
Quantité
100 μg
Fiche technique
Fiche technique
ABCC2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953980
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5652070
Quantité
96 tests
Fiche technique
Fiche technique
ABCC2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305455
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7407940
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ABCC2
: "Stimulatory effect of CSE-generated H2S on hepatic mitochondrial biogenesis and the underlying mechanisms." dans: Nitric oxide : biology and chemistry, Vol. 58, pp. 67-76, (2016) (PubMed).: "Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes." dans: Biomaterials, Vol. 34, Issue 18, pp. 4452-65, (2013) (PubMed).
: "Expression in human endothelial cells of ADP-ribosylation factors, 20-kDa guanine nucleotide-binding proteins involved in the initiation of vesicular transport." dans: Journal of molecular and cellular cardiology, Vol. 28, Issue 9, pp. 1911-20, (1997) (PubMed).
: "Isolation of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP ribosylation factor (ARF) 1 and ARF3 that contains a Sec7-like domain." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 23, pp. 12856-60, (1996) (PubMed).
: "Phospholipase D: a downstream effector of ARF in granulocytes." dans: Science (New York, N.Y.), Vol. 263, Issue 5146, pp. 523-6, (1994) (PubMed).
: "ADP-ribosylation factors, 20,000 M(r) guanine nucleotide-binding protein activators of cholera toxin and components of intracellular vesicular transport systems." dans: Cellular signalling, Vol. 5, Issue 4, pp. 367-79, (1993) (PubMed).
: "Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin." dans: The Journal of biological chemistry, Vol. 259, Issue 10, pp. 6228-34, (1984) (PubMed).
Synonymes et noms alternatifs relatifs à ABCC2
ATP binding cassette subfamily C member 2 (ABCC2), ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2), ATP binding cassette subfamily C member 2 (Abcc2), ABC30, Abc30, AI173996, CMOAT, Cmoat, cMRP, DJS, MRP2, Mrp2Protein level used designations for ABCC2
- ATP-binding cassette sub-family C member 2
- canalicular multidrug resistance protein
- canalicular multispecific organic anion transporter 1
- multidrug resistance-associated protein 2
- multidrug resistance protein 2
- ATP-binding cassette, sub-family C (CFTR/MRP), member 2
- calicular multispecific organic anion transporter
- multidrug resistance associated protein 2
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