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ABCC4 Produits

(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined\; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories ABCC4 en vedette

ABCC4 Anticorps

High quality antibodies with extensive validation data.

ABCC4 Kits ELISA

Reliable ELISA kits for a wide range of species.

ABCC4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ABCC4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (1)
  • (6)
N° du produit ABIN1724860
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (4)
  • (4)
N° du produit ABIN185302
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
N° du produit ABIN564442
Quantité 100 μg
Fiche technique Fiche technique

ABCC4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965075
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953982
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5652072
Quantité 96 tests
Fiche technique Fiche technique

ABCC4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305457
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7407946
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3109892
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ABCC4

Al-Abdulla, Perez-Silva, Lozano, Macias, Herraez, Abad, Segues, Bujanda, Briz, Marin: "Sensitizing gastric adenocarcinoma to chemotherapy by pharmacological manipulation of drug transporters." dans: Biochemical pharmacology, Vol. 171, pp. 113682, (2020) (PubMed).

Nagy, Hollema, Andrei, Jurdzinski, Kuipers, Hoek, Tietge: "The Origin of Follicular Bile Acids in the Human Ovary." dans: The American journal of pathology, (2019) (PubMed).

Zhang, Dong, Wang, Ma, Wang, Wu: "Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay." dans: Molecular pharmaceutics, Vol. 12, Issue 4, pp. 1268-78, (2016) (PubMed).

Li, Sun, Zhang, Wang, Wu: "Efflux transport of chrysin and apigenin sulfates in HEK293 cells overexpressing SULT1A3: The role of multidrug resistance-associated protein 4 (MRP4/ABCC4)." dans: Biochemical pharmacology, Vol. 98, Issue 1, pp. 203-14, (2016) (PubMed).

Quan, Wang, Dong, Zhang, Wu: "Characterization of chrysin glucuronidation in UGT1A1-overexpressing HeLa cells: elucidating the transporters responsible for efflux of glucuronide." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 43, Issue 4, pp. 433-43, (2015) (PubMed).

Hiasa, Togawa, Miyaji, Omote, Yamamoto, Moriyama: "Essential role of vesicular nucleotide transporter in vesicular storage and release of nucleotides in platelets." dans: Physiological reports, Vol. 2, Issue 6, (2014) (PubMed).

Domingue, Ao, Sarathy, George, Alrefai, Nelson, Rao: "HEK-293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl- transport." dans: Physiological reports, Vol. 2, Issue 9, (2014) (PubMed).

Gori, Rodriguez, Pellegrini, Achtari, Hornung, Chardonnens, Wunder, Fiche, Canny: "Augmented epithelial multidrug resistance-associated protein 4 expression in peritoneal endometriosis: regulation by lipoxin A(4)." dans: Fertility and sterility, Vol. 99, Issue 7, pp. 1965-73.e2, (2013) (PubMed).

Montani, Hermanns, Herrmanns, Müntener, Wild, Sulser, Kristiansen: "Multidrug resistance protein 4 (MRP4) expression in prostate cancer is associated with androgen signaling and decreases with tumor progression." dans: Virchows Archiv : an international journal of pathology, Vol. 462, Issue 4, pp. 437-43, (2013) (PubMed).

Brachs, Lang, Buslei, Purohit, Fürnrohr, Kalbacher, Jäck, Mielenz: "Monoclonal antibodies to discriminate the EF hand containing calcium binding adaptor proteins EFhd1 and EFhd2." dans: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 4, pp. 237-45, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à ABCC4

ATP binding cassette subfamily C member 4 (ABCC4), multidrug resistance-associated protein 4 (LOC515333), multidrug resistance-associated protein 4 (LOC616707), multidrug resistance-associated protein 4 (LOC695407), ATP binding cassette subfamily C member 4 (abcc4), ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), ATP binding cassette subfamily C member 4 (Abcc4), D630049P08Rik, EST170205, MOAT-B, MOATB, MRP4, Mrp4

Protein level used designations for ABCC4

  • multidrug resistance-associated protein 4
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • ATP-binding cassette protein C4-like
  • multidrug resistance-associated protein 4-like
  • ATP-binding cassette sub-family C member 4
  • MRP/cMOAT-related ABC transporter
  • bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)
  • canalicular multispecific organic anion transporter (ABC superfamily)
  • multi-specific organic anion transporter B
  • multispecific organic anion transporter B
  • ABC-tranporter
  • ATP-binding cassette protein C4
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