Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ABCC5 Produits

(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories ABCC5 en vedette

ABCC5 Anticorps

High quality antibodies with extensive validation data.

ABCC5 Kits ELISA

Reliable ELISA kits for a wide range of species.

ABCC5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ABCC5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (5)
N° du produit ABIN302162
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
  • (3)
N° du produit ABIN6266184
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7160318
Quantité 100 μg
Fiche technique Fiche technique

ABCC5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964517
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953382
Quantité 96 tests
Fiche technique Fiche technique

ABCC5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305459
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305461
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7407949
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ABCC5

Xiang, Ye, Huang, Yu, Chen, Deng, Zhang, Lou, Zhang, Shi, Chen, Zhou: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).

Naud, Laurin, Michaud, Beauchemin, Leblond, Pichette: "Effects of chronic renal failure on brain drug transporters in rats." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 1, pp. 39-46, (2011) (PubMed).

Meyer Zu Schwabedissen, Grube, Heydrich, Linnemann, Fusch, Kroemer, Jedlitschky et al.: "Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ..." dans: The American journal of pathology, Vol. 166, Issue 1, pp. 39-48, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à ABCC5

ATP binding cassette subfamily C member 5 (ABCC5), ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5), ATP binding cassette subfamily C member 5 (Abcc5), ATP binding cassette subfamily C member 5 L homeolog (abcc5.L), 2900011L11Rik, ABC33, abc33, abcc5, Abcc5a, Abcc5b, AI132311, EST277145, MOAT-C, moat-c, MOATC, moatc, MRP5, Mrp5, mrp5, pABC11, pabc11, SMRP, smrp

Protein level used designations for ABCC5

  • ATP-binding cassette sub-family C member 5
  • canalicular multispecific organic anion transporter C
  • multi-specific organic anion transporter C
  • multidrug resistance-associated protein 5
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 5a
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 5b
  • ATP-binding cassette, sub-family C, member 5
  • MOAT-C
  • SMRP
  • ATP-binding cassette sub-family C (CFTR/MRP) member 5a
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 5
  • ATP binding cassette subfamily C member 5 L homeolog
Vous êtes ici:
Support technique