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ABCG5 Produits

(ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))

Catégories

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].

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Catégories ABCG5 en vedette

ABCG5 Anticorps

High quality antibodies with extensive validation data.

ABCG5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ABCG5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (2)
  • (7)
N° du produit ABIN1724857
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7144938
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (2)
  • (3)
N° du produit ABIN708371
Quantité 100 μL
Fiche technique Fiche technique

ABCG5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7419754
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3118046
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3128146
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ABCG5

Chen, Wu: "Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice." dans: Gastroenterology research and practice, Vol. 2020, pp. 1343969, (2020) (PubMed).

Ahn, Jun, Jang, Lee, Shin: "Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease." dans: The Korean journal of internal medicine, (2018) (PubMed).

Zhong, Sun, Ma, Zhu, Yang, Wei, Zeng, Zhang, Liu, Li, Chen, Yu, Song: "Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice." dans: Scientific reports, Vol. 5, pp. 10512, (2015) (PubMed).

Wang, Xiaoling, Pingting, Shuqiang, Yuaner: "Chronic unpredictable mild stress combined with a high-fat diets aggravates atherosclerosis in rats." dans: Lipids in health and disease, Vol. 13, pp. 77, (2014) (PubMed).

Ahn, Jang, Jun, Lee, Shin: "Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease." dans: Digestive diseases and sciences, Vol. 59, Issue 12, pp. 2975-82, (2014) (PubMed).

Huang, Wang, Quan, Wang, Yang, Zhong: "Lactobacillus acidophilus ATCC 4356 prevents atherosclerosis via inhibition of intestinal cholesterol absorption in apolipoprotein E-knockout mice." dans: Applied and environmental microbiology, Vol. 80, Issue 24, pp. 7496-504, (2014) (PubMed).

Li, Yin, Wei, Yan, Aung, Wu, Wu, Lin, Liu, Pan: "ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." dans: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).

Jakulj, Vissers, Tanck, Hutten, Stellaard, Kastelein, Dallinga-Thie: "ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis." dans: Journal of lipid research, Vol. 51, Issue 10, pp. 3016-23, (2010) (PubMed).

Johnson, Lee, Pickert, Urbatsch: "Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8." dans: Biochemistry, Vol. 49, Issue 16, pp. 3403-11, (2010) (PubMed).

Lee, Lu, Hazard, Yu, Shulenin, Hidaka, Kojima, Allikmets, Sakuma, Pegoraro, Srivastava, Salen, Dean, Patel: "Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption." dans: Nature genetics, Vol. 27, Issue 1, pp. 79-83, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à ABCG5

ATP binding cassette subfamily G member 5 (ABCG5), ATP-binding cassette, sub-family G (WHITE), member 5 (abcg5), ABC transporter G family protein (abcG5), ATP binding cassette subfamily G member 5 (abcg5), ATP-binding cassette, sub-family G (WHITE), member 5 (ABCG5), ATP binding cassette subfamily G member 5 (Abcg5), AW112016, cmp, DDBDRAFT_0205617, DDBDRAFT_0215344, DDB_0205617, DDB_0215344, sterolin-1, STSL, trac

Protein level used designations for ABCG5

  • ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1)
  • ATP-binding cassette sub-family G member 5
  • sterolin 1
  • ATP-binding cassette transporter
  • ATP-binding cassette, sub-family G (WHITE), member 5
  • ATP-binding cassette sub-family G member 5-like
  • ATP-binding cassette, subfamily G, member 5
  • sterolin-1
  • ATP-binding cassette sub-family G (WHITE) member 5 (sterolin 1)
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