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ABCG8 Produits

(ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].

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Catégories ABCG8 en vedette

ABCG8 Anticorps

High quality antibodies with extensive validation data.

ABCG8 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ABCG8 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (5)
N° du produit ABIN3022643
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7144942
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (3)
N° du produit ABIN6259696
Quantité 100 μL
Fiche technique Fiche technique

ABCG8 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7419505
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7419508
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3129571
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ABCG8

Chen, Wu: "Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice." dans: Gastroenterology research and practice, Vol. 2020, pp. 1343969, (2020) (PubMed).

Li, Kabir, Tietelman, Huan, Fan, Worgall, Jiang: "Sphingolipid de novo biosynthesis is essential for intestine cell survival and barrier function." dans: Cell death & disease, Vol. 9, Issue 2, pp. 173, (2019) (PubMed).

Ahn, Jun, Jang, Lee, Shin: "Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease." dans: The Korean journal of internal medicine, (2018) (PubMed).

Heverin, Ali, Olin, Tillander, Joibari, Makoveichuk, Leitersdorf, Warner, Olivercrona, Gustafsson, Björkhem: "On the regulatory importance of 27-hydroxycholesterol in mouse liver." dans: The Journal of steroid biochemistry and molecular biology, (2016) (PubMed).

Sachdev, Leopold, Bauer, Patankar, Iqbal, Obrowsky, Boverhof, Doktorova, Scheicher, Goeritzer, Kolb, Turnbull, Zimmer, Hoefler, Hussain, Groen, Kratky: "Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism." dans: Biochimica et biophysica acta, Vol. 1861, Issue 9 Pt A, pp. 1132-41, (2016) (PubMed).

Maqdasy, El Hajjaji, Baptissart, Viennois, Oumeddour, Brugnon, Trousson, Tauveron, Volle, Lobaccaro, Baron: "Identification of the Functions of Liver X Receptor-β in Sertoli Cells Using a Targeted Expression-Rescue Model." dans: Endocrinology, Vol. 156, Issue 12, pp. 4545-57, (2015) (PubMed).

Xie, Fung, Newberry, Kennedy, Luo, Crooke, Graham, Davidson: "Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice." dans: Journal of lipid research, Vol. 55, Issue 3, pp. 540-8, (2014) (PubMed).

Suzuki, Shuto, Sato, Kaneko, Takada, Suico, Cyr, Suzuki, Kai: "Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter." dans: Scientific reports, Vol. 4, pp. 4258, (2014) (PubMed).

Huang, Wang, Quan, Wang, Yang, Zhong: "Lactobacillus acidophilus ATCC 4356 prevents atherosclerosis via inhibition of intestinal cholesterol absorption in apolipoprotein E-knockout mice." dans: Applied and environmental microbiology, Vol. 80, Issue 24, pp. 7496-504, (2014) (PubMed).

Ahn, Jang, Jun, Lee, Shin: "Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease." dans: Digestive diseases and sciences, Vol. 59, Issue 12, pp. 2975-82, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à ABCG8

ATP binding cassette subfamily G member 8 (ABCG8), ATP-binding cassette sub-family G member 8 (PTRG_02054), ABC transporter G family protein (abcG8), ATP-binding cassette, sub-family G (WHITE), member 8 (abcg8), ATP binding cassette subfamily G member 8 (Abcg8), 1300003C16Rik, AI114946, DDBDRAFT_0167690, DDBDRAFT_0191232, DDB_0167690, DDB_0191232, GBD4, sterolin-2, STSL, zgc:172358

Protein level used designations for ABCG8

  • ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)
  • sterolin 2
  • ATP-binding cassette sub-family G member 8
  • sterolin-2
  • ATP-binding cassette, sub-family G (WHITE), member 8
  • ATP-binding cassette sub-family G member 8-like
  • ATP-binding cassette, subfamily G, member 8
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