ACLY Produits
(ATP Citrate Lyase (ACLY))
Catégories
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Catégories ACLY en vedette
ACLY Anticorps
High quality antibodies with extensive validation data.
ACLY Kits ELISA
Reliable ELISA kits for a wide range of species.
ACLY Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ACLY recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (7)
N° du produit
ABIN1098143
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN7265716
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP
Validations
- (5)
N° du produit
ABIN6136002
Quantité
100 μL
Fiche technique
Fiche technique
ACLY recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965053
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965052
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965051
Quantité
96 tests
Fiche technique
Fiche technique
ACLY recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121924
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
N° du produit
ABIN7194322
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3088222
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ACLY
: "mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer." dans: Oncotarget, Vol. 7, Issue 18, pp. 25224-40, (2018) (PubMed).: "The contribution of the citrate pathway to oxidative stress in Down syndrome." dans: Immunology, Vol. 149, Issue 4, pp. 423-431, (2016) (PubMed).
: "Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells." dans: International journal of cancer, Vol. 135, Issue 1, pp. 37-47, (2014) (PubMed).
: "Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth." dans: Cancer letters, Vol. 349, Issue 1, pp. 15-25, (2014) (PubMed).
: "ATP-citrate lyase is essential for macrophage inflammatory response." dans: Biochemical and biophysical research communications, Vol. 440, Issue 1, pp. 105-11, (2013) (PubMed).
: "ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells." dans: The Journal of biological chemistry, Vol. 285, Issue 42, pp. 32606-15, (2010) (PubMed).
: "Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas." dans: International journal of cancer. Journal international du cancer, Vol. 126, Issue 10, pp. 2282-95, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à ACLY
ATP citrate lyase (ACLY), ATP citrate lyase S homeolog (acly.S), ATP-citrate synthase (LOC587157), ATP citrate lyase (acly), ATP citrate lyase (ATPCL), ATP-citrate synthase (LOC5564509), citrate synthase, mitochondrial (CpipJ_CPIJ010291), ATP-citrate synthase (Bm1_26245), atp-citrate synthase (ACL), ATP citrate lyase (Acly), ATP citrate lyase a (aclya), A730098H14Rik, ACL, ACLY, acly, anon-WO0140519.179, ATPCL, AW538652, BcDNA:LD21334, cb722, CG8322, CLATP, Clatp, dATPCL, DDBDRAFT_0205389, DDBDRAFT_0235360, DDB_0205389, DDB_0235360, DmATPCL, Dmel\\CG8322, l(2)01466, l(2)k09217, n(2)k09217, zgc:92008Protein level used designations for ACLY
- ATP citrate lyase
- ATP citrate synthase
- ATP-citrate synthase-like
- ATP-citrate lyase
- ATPCL-PD
- ATPCL-PE
- ATPCL-PF
- CG8322-PD
- CG8322-PE
- CG8322-PF
- ATP-citrate synthase
- citrate synthase, mitochondrial
- atp-citrate synthase
- ATP-citrate (pro-S-)-lyase
- citrate cleavage enzyme
Avez-vous cherché autre chose?
- ACIN1
- Acid Phosphatase
- Acid Invertase
- AChR Ab
- ACHB3
- Achaete-scute complex protein T5
- Achaete-Scute Complex Homolog 1 (Drosophila)
- Achaete
- Acetylcholinesterase
- Acetylcholine
- Acetylated Lysine
- Acetyl-CoA Carboxylase beta
- Acetyl-CoA Carboxylase alpha
- Acetyl-CoA Carboxylase
- Acetyl-CoA
- Acetoin Reductase
- Acetate Kinase
- ACER3
- ACER2
- ACER1
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