ACVR1 Produits
(Activin Receptor Type I (ACRV1))
Catégories
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008].
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Catégories ACVR1 en vedette
ACVR1 Anticorps
High quality antibodies with extensive validation data.
ACVR1 Kits ELISA
Reliable ELISA kits for a wide range of species.
ACVR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ACVR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (4)
N° du produit
ABIN392240
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
- (3)
N° du produit
ABIN391156
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
N° du produit
ABIN657718
Quantité
400 μL
Fiche technique
Fiche technique
ACVR1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953435
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1742678
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Sheep
Analytical Method
Validations
N° du produit
ABIN1773582
Quantité
96 tests
Fiche technique
Fiche technique
ACVR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305799
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305801
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7194135
Quantité
200 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ACVR1
: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." dans: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).: "Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal." dans: Cell death & disease, Vol. 9, Issue 9, pp. 927, (2018) (PubMed).
: "Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2." dans: Biochemical and biophysical research communications, Vol. 455, Issue 3-4, pp. 347-52, (2014) (PubMed).
: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." dans: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).
: "BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury." dans: American journal of physiology. Renal physiology, Vol. 293, Issue 5, pp. F1641-8, (2007) (PubMed).
: "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva." dans: Nature genetics, Vol. 38, Issue 5, pp. 525-7, (2006) (PubMed).
: "A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma." dans: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 9, pp. 3584-91, (2006) (PubMed).
: "EphB4 provides survival advantage to squamous cell carcinoma of the head and neck." dans: International journal of cancer, Vol. 119, Issue 6, pp. 1236-48, (2006) (PubMed).
: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." dans: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).
: "The distribution of activin and activin receptors in gestational tissues across human pregnancy and during labour." dans: Placenta, Vol. 23, Issue 4, pp. 294-302, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à ACVR1
activin A receptor type 1 (ACVR1), activin A receptor type 1 (Acvr1), activin A receptor, type 1 (Acvr1), activin A receptor type 1 S homeolog (acvr1.S), ActR-I, ActR-IA, ACTRI, actri, ActRIA, Acvr, acvr1, acvr1-a, acvr1-b, ACVR1A, acvr1a, ACVRLK2, Acvrlk2, acvrlk2, Alk-2, alk-2, ALK2, alk2, Alk8, alk8, D330013D15Rik, FOP, fop, sax, SKR1, skr1, Tsk7L, TSRI, tsri, xALK-2Protein level used designations for ACVR1
- TGF-B superfamily receptor type I
- activin A receptor, type II-like kinase 2
- activin receptor type I
- activin receptor type-1
- activin receptor-like kinase 2
- hydroxyalkyl-protein kinase
- serine/threonine-protein kinase receptor R1
- ACTR-I
- SKR1
- TSR-I
- activin A receptor, type 1
- activin type I receptor
- type I TGF B receptor
- activin A receptor, type I
- activin receptor type IA
- TSK-7L
- activin A receptor type 1 S homeolog
- activin A receptor type I S homeolog
- activin receptor like kinase-2
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