ACVR2B Produits
(Activin A Receptor, Type IIB (ACVR2B))
Catégories
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008].
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Catégories ACVR2B en vedette
ACVR2B Anticorps
High quality antibodies with extensive validation data.
ACVR2B Kits ELISA
Reliable ELISA kits for a wide range of species.
ACVR2B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ACVR2B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Sheep, Zebrafish (Danio rerio)
Application
WB
Validations
- (5)
N° du produit
ABIN2782110
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
- (3)
N° du produit
ABIN1714650
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
N° du produit
ABIN391162
Quantité
400 μL
Fiche technique
Fiche technique
ACVR2B recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953430
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4881730
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6385086
Quantité
96 tests
Fiche technique
Fiche technique
ACVR2B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305815
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305817
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7320385
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ACVR2B
: "Modulation of noncanonical TGF-? signaling prevents cleft palate in Tgfbr2 mutant mice." dans: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 873-85, (2012) (PubMed).: "Myostatin is associated with age-related human muscle stem cell dysfunction." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 6, pp. 2509-21, (2012) (PubMed).
: "Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation." dans: Developmental biology, Vol. 266, Issue 2, pp. 334-45, (2004) (PubMed).
: "An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors." dans: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28036-44, (2004) (PubMed).
: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." dans: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à ACVR2B
activin A receptor type 2B (ACVR2B), activin A receptor type 2B (acvr2b), activin A receptor type 2B L homeolog (acvr2b.L), activin A receptor type 2B (Acvr2b), activin A receptor type 2Ba (acvr2ba), activin receptor IIB (Acvr2b), actr-iib, ActR-IIB, actr2b, actriib, ACTRIIB, ActRIIB, actrIIb, ACVR2B, HTX4, wu:fj97d11, XAR1Protein level used designations for ACVR2B
- activin A receptor, type IIB
- activin receptor type IIB
- activin receptor type-2B-like
- activin type IIB receptor
- activin receptor type-2B
- ACTR-IIB
- testicular activin receptor IIB
- ActRIIB type II activin receptor B
- Activine receptor 2b (transmembrane serine kinase)
- activin receptor IIB
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