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ACVRL1 Produits

(Activin A Receptor Type II-Like 1 (ACVRL1))
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008].

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Catégories ACVRL1 en vedette

ACVRL1 Anticorps

High quality antibodies with extensive validation data.

ACVRL1 Kits ELISA

Reliable ELISA kits for a wide range of species.

ACVRL1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ACVRL1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (4)
  • (5)
N° du produit ABIN392241
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (7)
N° du produit ABIN3029853
Quantité 0.4 mL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7183058
Quantité 100 μL
Fiche technique Fiche technique

ACVRL1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953428
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5510685
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5510686
Quantité 96 tests
Fiche technique Fiche technique

ACVRL1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7273821
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Human Cells
Validations
  • (1)
N° du produit ABIN7320736
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305819
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ACVRL1

Chen, Qin, Li, Wang, Dahlman, Malagon-Lopez, Gujja, Cilfone, Kauffman, Sun, Sun, Zhang, Aryal, Canfran-Duque, Liu, Kusters, Sehgal, Jiao, Anderson, Gulcher, Fernandez-Hernando, Lutgens, Schwartz et al.: "Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis. ..." dans: Nature metabolism, Vol. 1, Issue 9, pp. 912-926, (2019) (PubMed).

Muñoz-Félix, Cuesta, Perretta-Tejedor, Subileau, López-Hernández, López-Novoa, Martínez-Salgado: "Identification of bone morphogenetic protein 9 (BMP9) as a novel profibrotic factor in vitro." dans: Cellular signalling, Vol. 28, Issue 9, pp. 1252-61, (2017) (PubMed).

Sanz-Ramos, Dotor, Izal-Azcárate: "The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes." dans: Cellular & molecular biology letters, Vol. 19, Issue 4, pp. 659-74, (2014) (PubMed).

Antonov, Antonova, Fujii, ten Dijke, Handa, Catravas, Verin: "Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90." dans: Journal of cellular physiology, Vol. 227, Issue 2, pp. 759-71, (2011) (PubMed).

Cunha, Pardali, Thorikay, Anderberg, Hawinkels, Goumans, Seehra, Heldin, ten Dijke, Pietras: "Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis." dans: The Journal of experimental medicine, Vol. 207, Issue 1, pp. 85-100, (2010) (PubMed).

Finnson, Parker, ten Dijke, Thorikay, Philip: "ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 23, Issue 6, pp. 896-906, (2008) (PubMed).

Yu, Pisitkun, Wang, Shen, Knepper: "LC-MS/MS analysis of apical and basolateral plasma membranes of rat renal collecting duct cells." dans: Molecular & cellular proteomics : MCP, Vol. 5, Issue 11, pp. 2131-45, (2006) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Berg, Gallione, Stenzel, Johnson, Allen, Schwartz, Jackson, Porteous, Marchuk: "The activin receptor-like kinase 1 gene: genomic structure and mutations in hereditary hemorrhagic telangiectasia type 2." dans: American journal of human genetics, Vol. 61, Issue 1, pp. 60-7, (1997) (PubMed).

Johnson, Berg, Baldwin, Gallione, Marondel, Yoon, Stenzel, Speer, Pericak-Vance, Diamond, Guttmacher, Jackson, Attisano, Kucherlapati, Porteous, Marchuk: "Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2." dans: Nature genetics, Vol. 13, Issue 2, pp. 189-95, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à ACVRL1

activin A receptor like type 1 (ACVRL1), activin A receptor type II-like 1 (ACVRL1), activin A receptor like type 1 (acvrl1), activin A receptor like type 1 (Acvrl1), activin A receptor, type II-like 1 (Acvrl1), ACVRL1, ACVRLK1, Acvrlk1, AI115505, AI427544, ALK-1, alk1, ALK1, Alk1, HHT, HHT2, hm:zehn1109, ORW2, R-3, R3, SETHKIR, SKR3, TSR-I, vgb, zehn1109

Protein level used designations for ACVRL1

  • activin A receptor type II-like 1
  • serine/threonine-protein kinase receptor R3
  • serine/threonine-protein kinase receptor R3-like
  • activin receptor-like kinase 1
  • vbg
  • violet beauregarde
  • TGF-B superfamily receptor type I
  • activin A receptor, type II-like kinase 1
  • Activin receptor like kinase 1
  • SKR3
  • TSR-I
  • ALK-1
  • activin receptor-like kinase-1
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