ShK

N° du produit ABIN1540127

Détail du produit

Antigène: Toxin ShK (Stoichactishelianthus potassium-channel reduced)

Application: Blocking Reagent (BR)

Fonction: ShK is a Kv1.3 channel selective blocker

Séquence: Arg-Ser-Cys3-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys12-Thr-Ala-Phe-Gln-Cys17-Lys-His-Ser-Met-Lys-Tyr-Arg-Leu-Ser-Phe-Cys28-Arg-Lys-Thr-Cys32-Gly-Thr-Cys35-OHDisulfid e bonds between Cys3-Cys35, Cys12-Cys28 and Cys17-Cys32

Information d'application

Restrictions: For Research Use only

Stockage

Détail du antigène

Antigène: Toxin ShK (Stoichactishelianthus potassium-channel reduced)

Sujet: ShK has been isolated from the venom of the Carribean seaanemone Stoichactis helianthus. This toxin inhibits voltagedependentpotassium channels. It blocks Kv1.3 (KCNA3)potently and also Kv1.1 (KCNA1), Kv1.4 (KCNA4), and Kv1.6(KCNA6) respectively with 11 pM,16 pM and 165 pM.

Poids moléculaire: 4054.85 Da