ADAM8 Produits
(ADAM Metallopeptidase Domain 8 (ADAM8))
Catégories
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009].
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Catégories ADAM8 en vedette
ADAM8 Anticorps
High quality antibodies with extensive validation data.
ADAM8 Kits ELISA
Reliable ELISA kits for a wide range of species.
ADAM8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ADAM8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, FACS, ICC
Validations
- (6)
N° du produit
ABIN7193315
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
- (1)
N° du produit
ABIN1866534
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7150062
Quantité
100 μg
Fiche technique
Fiche technique
ADAM8 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
- (1)
N° du produit
ABIN415444
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6961974
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953454
Quantité
96 tests
Fiche technique
Fiche technique
ADAM8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7273801
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7273803
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121692
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ADAM8
: "Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans." dans: Atherosclerosis, Vol. 286, pp. 163-171, (2019) (PubMed).: "A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric Cancer." dans: Yonsei medical journal, Vol. 60, Issue 8, pp. 713-719, (2019) (PubMed).
: "miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells." dans: Breast cancer research : BCR, Vol. 18, Issue 1, pp. 40, (2016) (PubMed).
: "ADAM8 as a drug target in pancreatic cancer." dans: Nature communications, Vol. 6, pp. 6175, (2015) (PubMed).
: "Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 12, pp. 8053-63, (2007) (PubMed).
: "Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes." dans: American journal of respiratory cell and molecular biology, Vol. 31, Issue 4, pp. 413-22, (2004) (PubMed).
: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." dans: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, (1999) (PubMed).
: "Defective angiogenesis in mice lacking endoglin." dans: Science (New York, N.Y.), Vol. 284, Issue 5419, pp. 1534-7, (1999) (PubMed).
: "CD156 (human ADAM8): expression, primary amino acid sequence, and gene location." dans: Genomics, Vol. 41, Issue 1, pp. 56-62, (1997) (PubMed).
: "Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions." dans: European journal of immunology, Vol. 23, Issue 9, pp. 2340-5, (1993) (PubMed).
Synonymes et noms alternatifs relatifs à ADAM8
ADAM metallopeptidase domain 8 (ADAM8), a disintegrin and metalloproteinase domain 8 (LOC100304737), a disintegrin and metallopeptidase domain 8 (Adam8), ADAM metallopeptidase domain 8a (adam8a), ADAM metallopeptidase domain 8 (Adam8), a disintegrin and metalloproteinase domain 8 (adam8), adam8, ADAM8, CD156, CD156a, E430039A18Rik, MS2, reprolysin, RGD1566394, si:zc217g15.7, zgc:64059Protein level used designations for ADAM8
- a disintegrin and metalloproteinase domain 8
- cell surface antigen MS2
- disintegrin and metalloproteinase domain-containing protein 8
- human leukocyte differentiation antigen
- ADAM 8
- a disintegrin and metalloprotease domain (ADAM) 8
- a disintegrin and metalloprotease domain 8
- macrophage cysteine-rich glycoprotein
- CD156a
- metalloprotease
- ADAM metallopeptidase domain 8
- a disintegrin and metallopeptidase domain 8
- disintegrin and metalloproteinase domain-containing protein 8-like
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