ADAMTS4 Produits
(ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
Catégories
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq, Jul 2008].
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Catégories ADAMTS4 en vedette
ADAMTS4 Anticorps
High quality antibodies with extensive validation data.
ADAMTS4 Kits ELISA
Reliable ELISA kits for a wide range of species.
ADAMTS4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ADAMTS4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (6)
N° du produit
ABIN7072947
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
N° du produit
ABIN7142886
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
- (3)
N° du produit
ABIN391642
Quantité
400 μL
Fiche technique
Fiche technique
ADAMTS4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6974698
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (8)
- (1)
N° du produit
ABIN6953462
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rabbit
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953464
Quantité
96 tests
Fiche technique
Fiche technique
ADAMTS4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305903
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305901
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7409560
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ADAMTS4
: "MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1β-Induced Catabolism in Human Articular Chondrocytes." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 1, pp. 38-52, (2018) (PubMed).: "AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice." dans: Scientific reports, Vol. 7, pp. 43245, (2017) (PubMed).
: "VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts." dans: Journal of cellular and molecular medicine, Vol. 20, Issue 4, pp. 678-87, (2016) (PubMed).
: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." dans: International wound journal, (2016) (PubMed).
: "Parathyroid hormone(1-34) exhibits more comprehensive effects than celecoxib in cartilage metabolism and maintaining subchondral bone micro-architecture in meniscectomized guinea pigs." dans: Osteoarthritis and cartilage, Vol. 24, Issue 6, pp. 1103-12, (2016) (PubMed).
: "Healthy and Osteoarthritic Synovial Fibroblasts Produce a Disintegrin and Metalloproteinase with Thrombospondin Motifs 4, 5, 7, and 12: Induction by IL-1β and Fibronectin and Contribution to ..." dans: The American journal of pathology, Vol. 186, Issue 9, pp. 2449-61, (2016) (PubMed).
: "Protective effect of calcitonin on lumbar fusion-induced adjacent-segment disc degeneration in ovariectomized rat." dans: BMC musculoskeletal disorders, Vol. 16, pp. 342, (2016) (PubMed).
: "A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes." dans: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, (2015) (PubMed).
: "Lack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium." dans: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 23, Issue 11, pp. 2045-57, (2015) (PubMed).
: "Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases." dans: Archives of pathology & laboratory medicine, Vol. 138, Issue 5, pp. 643-50, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à ADAMTS4
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4), ADAM metallopeptidase with thrombospondin type 1 motif 4 (ADAMTS4), ADAM metallopeptidase with thrombospondin type 1 motif, 4 (Adamts4), ADAM metallopeptidase with thrombospondin type 1 motif 4 (Adamts4), 3830423K05, ADAM-TS4, ADAMTS-2, ADAMTS-4, ADAMTS4, ADMP-1, mKIAA0688Protein level used designations for ADAMTS4
- A disintegrin and metalloproteinase with thrombospondin motifs 4
- ADAM-TS 4
- ADAMTS-4
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4
- aggrecanase-1
- ADAM-TS4
- Aggrecanase
- a disintegrin and metallopeptidase with thrombospondin motifs 4
- a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
- ADMP-1
- ADAM metallopeptidase with thrombospondin type 1 motif, 4
- A disintegrin and metalloproteinase with thrombospondin motifs 4-like
- disintegrin and metalloproteinase with thrombospondin motifs 2
- a disintegrin and metalloproteinase with thrombospondin motifs 4
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