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ADD3 Produits

(Adducin 3 (Gamma) (ADD3))

Catégories

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known. [provided by RefSeq, Jul 2008].

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Catégories ADD3 en vedette

ADD3 Anticorps

High quality antibodies with extensive validation data.

ADD3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ADD3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (5)
N° du produit ABIN559788
Quantité 50 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC, ICC
Validations
  • (4)
N° du produit ABIN6257585
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (2)
N° du produit ABIN7185801
Quantité 100 μg
Fiche technique Fiche technique

ADD3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6208555
Quantité 96 tests
Fiche technique Fiche technique

ADD3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305971
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7421470
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2721672
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ADD3

Fallon, Moreau, Croft, Labib, Gu, Fon: "Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain." dans: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 486-91, (2002) (PubMed).

Bowery, Brown: "The cloning of GABA(B) receptors." dans: Nature, Vol. 386, Issue 6622, pp. 223-4, (1997) (PubMed).

Dong, OBrien, Fung, Lanahan, Worley, Huganir: "GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors." dans: Nature, Vol. 386, Issue 6622, pp. 279-84, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à ADD3

adducin 3 (gamma) (ADD3), adducin 3 (add3), adducin 3 (ADD3), adducin 3 L homeolog (add3.L), adducin 3 (gamma) (Add3), adducin 3 (Add3), add3, ADD3, ADDL, AI463285, DKFZp459E0630, gamma-adducin, MGC89418, R75380

Protein level used designations for ADD3

  • gamma-adducin
  • adducin 3 (gamma)
  • adducin 3 gamma
  • gamma-adducin-like
  • adducin-like protein 70
  • cytoskeletal protein
  • potein kinase C binding protein 35H
  • protein kinase C-binding protein 35H
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