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AGAP2 Produits

(ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2))

Catégories

The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].

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Catégories AGAP2 en vedette

AGAP2 Anticorps

High quality antibodies with extensive validation data.

AGAP2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

AGAP2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN570975
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB
Validations
  • (2)
N° du produit ABIN654901
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Monkey
Application WB, IHC, IHC (p)
Validations
  • (2)
N° du produit ABIN960073
Quantité 100 μg
Fiche technique Fiche technique

AGAP2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6223198
Quantité 96 tests
Fiche technique Fiche technique

AGAP2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1344548
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3088375
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3135049
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits AGAP2

Liu, Jang, Liu, Cheng, Peng, Yepes, Li, Matthews, Watts, Asano, Hara-Nishimura, Luo, Ye: "Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase." dans: Molecular cell, Vol. 29, Issue 6, pp. 665-78, (2008) (PubMed).

Ahn, Rong, Kroll, Van Meir, Snyder, Ye: "PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion." dans: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 16441-51, (2004) (PubMed).

Hatziioannou, Perez-Caballero, Yang, Cowan, Bieniasz: "Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10774-9, (2004) (PubMed).

Stremlau, Owens, Perron, Kiessling, Autissier, Sodroski: "The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys." dans: Nature, Vol. 427, Issue 6977, pp. 848-53, (2004) (PubMed).

Xu, Yang, Moitra, Hashimoto, Rallabhandi, Kaul, Meroni, Jensen, Weissman, DArpa: "BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta." dans: Experimental cell research, Vol. 288, Issue 1, pp. 84-93, (2003) (PubMed).

Rong, Ahn, Huang, Nagata, Kalman, Kapp, Tu, Worley, Snyder, Ye: "PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis." dans: Nature neuroscience, Vol. 6, Issue 11, pp. 1153-61, (2003) (PubMed).

Ye, Hurt, Wu, Fang, Luo, Hong, Blackshaw, Ferris, Snyder: "Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N." dans: Cell, Vol. 103, Issue 6, pp. 919-30, (2001) (PubMed).

Jackson, Kearns, Theibert: "Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling." dans: Trends in biochemical sciences, Vol. 25, Issue 10, pp. 489-95, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à AGAP2

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (agap2), ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (Agap2), CENTG1, Centg1, GGAP2, mKIAA0167, PIKE, Pike, zgc:153779

Protein level used designations for AGAP2

  • arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
  • Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2
  • GTP-binding and GTPase activating protein 2
  • centaurin, gamma 1
  • cnt-g1
  • phosphatidylinositol 3-kinase enhancer
  • phosphatidylinositol-3-kinase enhancer
  • phosphoinositide 3-kinase enhancer
  • AGAP-2
  • PIKE
  • centaurin-gamma-1
  • nuclear GTPase PIKE
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