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Aggrecan Produits

(Aggrecan (ACAN))

Catégories

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008].

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Catégories Aggrecan en vedette

Aggrecan Anticorps

High quality antibodies with extensive validation data.

Aggrecan Kits ELISA

Reliable ELISA kits for a wide range of species.

Aggrecan Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Aggrecan recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7437053
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (1)
  • (2)
N° du produit ABIN7434326
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rabbit, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (6)
  • (2)
N° du produit ABIN673599
Quantité 100 μL
Fiche technique Fiche technique

Aggrecan recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (5)
N° du produit ABIN6730910
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6953560
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964680
Quantité 96 tests
Fiche technique Fiche technique

Aggrecan recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305600
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1305598
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
N° du produit ABIN7454069
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Aggrecan

Sun, Sun, Sun, Jiang, Lin, Kong, Li, Zhu, Huan, Zheng, Wang, Zou, Gao, Xu, Shi: "Tissue Renin-Angiotensin System (tRAS) Induce Intervertebral Disc Degeneration by Activating Oxidative Stress and Inflammatory Reaction." dans: Oxidative medicine and cellular longevity, Vol. 2021, pp. 3225439, (2022) (PubMed).

Sun, Zhu, Sun, Sun, Huan, Zhang, Lin, Zheng, Jiang, Luo, Xu, Shi: "Neuropeptide Y prevents nucleus pulposus cells from cell apoptosis and IL‑1β‑induced extracellular matrix degradation." dans: Cell cycle (Georgetown, Tex.), Vol. 20, Issue 10, pp. 960-977, (2022) (PubMed).

Song, Li, Sun, Zhao: "Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." dans: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).

Xuan, Hu, Geng, Song, Shen, Lei, Guan, Zhao, You: "Biofunctionalized chondrogenic shape-memory ternary scaffolds for efficient cell-free cartilage regeneration." dans: Acta biomaterialia, Vol. 105, pp. 97-110, (2021) (PubMed).

Luo, Huan, Lin, Kong, Sun, Li, Zhu, Sun, Xu, Sun, Duan, Shi: "Ulinastatin Ameliorates IL-1β-Induced Cell Dysfunction in Human Nucleus Pulposus Cells via Nrf2/NF-κB Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2021, pp. 5558687, (2021) (PubMed).

Szeremeta, Jura-Półtorak, Zoń-Giebel, Kopeć-Mędrek, Kucharz, Olczyk: "Aggrecan Turnover in Women with Rheumatoid Arthritis Treated with TNF-α Inhibitors." dans: Journal of clinical medicine, Vol. 9, Issue 5, (2020) (PubMed).

Yang, Zhu, Zhu, Feng, Gong, Chen, Chen: "17β-Estradiol/extrogen receptor β alleviates apoptosis and enhances matrix biosynthesis of nucleus pulposus cells through regulating oxidative damage under a high glucose condition." dans: Biomedicine & pharmacotherapy, Vol. 107, pp. 1004-1009, (2019) (PubMed).

Chen, Liu, Li, Wu: "Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system." dans: Cellular & molecular biology letters, Vol. 24, pp. 16, (2019) (PubMed).

Liu, Zhang, Zhang, Zhang, Du, Zhang, Zhang, Xu, Wu, Zhang, Li, Tan, Huang: "Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells." dans: Bioscience reports, Vol. 39, Issue 4, (2019) (PubMed).

Jiang, Fu, Song: "Responses of apoptosis and matrix metabolism of annulus fibrosus cells to different magnitudes of mechanical tension in vitro." dans: Bioscience reports, Vol. 39, Issue 2, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à Aggrecan

aggrecan (ACAN), aggrecan (Acan), aggrecan core protein (LOC100380783), aggrecan (AGC), Agc, AGC1, Agc1, AGCAN, b2b183Clo, cmd, CSPG1, Cspg1, CSPGCP, MSK16, SEDK

Protein level used designations for Aggrecan

  • aggrecan core protein
  • cartilage-specific proteoglycan core protein
  • chondroitin sulfate proteoglycan core protein 1
  • large aggregating proteoglycan
  • CSPCP
  • aggrecan 1
  • aggrecan, structural proteoglycan of cartilage
  • aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)
  • aggrecan epidermal growth factor-like domain-1
  • chondroitin sulfate proteoglycan core protein
  • cartilage aggregating proteoglycan
  • chondroitin sulfate proteoglycan 1
  • large aggregating proteoglycan, antigen
  • aggrecan
  • aggrecan core protein-like
  • aggrecan interglobular domain
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