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AICDA Produits

(Activation-Induced Cytidine Deaminase (AICDA))

Catégories

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009].

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Catégories AICDA en vedette

AICDA Anticorps

High quality antibodies with extensive validation data.

AICDA Kits ELISA

Reliable ELISA kits for a wide range of species.

AICDA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

AICDA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (4)
N° du produit ABIN2855890
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, EIA
Validations
  • (1)
  • (3)
N° du produit ABIN499233
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (2)
N° du produit ABIN3181420
Quantité 100 μL
Fiche technique Fiche technique

AICDA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953423
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Dog
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5593414
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6212552
Quantité 96 tests
Fiche technique Fiche technique

AICDA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN1098741
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1344654
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN2127824
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits AICDA

Milillo, Molinario, Costanzi, Vischini, La Carpia, La Greca, Rigante, Gambaro, Gurrieri, Sangiorgi: "Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura." dans: Journal of nephrology, Vol. 31, Issue 5, pp. 731-741, (2018) (PubMed).

Demberg, Mohanram, Musich, Brocca-Cofano, McKinnon, Venzon, Robert-Guroff: "Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection." dans: Virology, Vol. 484, pp. 323-333, (2015) (PubMed).

Cortizas, Zahn, Hajjar, Patenaude, Di Noia, Verdun: "Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 11, pp. 5751-63, (2013) (PubMed).

Ito, Murakami, Suzuki, Mochida, Suzuki, Ikebuchi, Yamaguchi, Mizuochi: "Enhanced expression of lymphomagenesis-related genes in peripheral blood B cells of chronic hepatitis C patients." dans: Clinical immunology (Orlando, Fla.), Vol. 135, Issue 3, pp. 459-65, (2010) (PubMed).

Kotani, Kakazu, Tsuruyama, Okazaki, Muramatsu, Kinoshita, Nagaoka, Yabe, Honjo: "Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 5, pp. 1616-20, (2007) (PubMed).

Crouch, Li, Takizawa, Fichtner-Feigl, Gourzi, Montaño, Feigenbaum, Wilson, Janz, Papavasiliou, Casellas: "Regulation of AID expression in the immune response." dans: The Journal of experimental medicine, Vol. 204, Issue 5, pp. 1145-56, (2007) (PubMed).

Larijani, Petrov, Kolenchenko, Berru, Krylov, Martin: "AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner." dans: Molecular and cellular biology, Vol. 27, Issue 1, pp. 20-30, (2006) (PubMed).

Besmer, Market, Papavasiliou: "The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination." dans: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4378-85, (2006) (PubMed).

Cascalho: "Advantages and disadvantages of cytidine deamination." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 11, pp. 6513-8, (2004) (PubMed).

Greeve, Philipsen, Krause, Klapper, Heidorn, Castle, Janda, Marcu, Parwaresch: "Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas." dans: Blood, Vol. 101, Issue 9, pp. 3574-80, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à AICDA

activation induced cytidine deaminase (AICDA), activation-induced cytidine deaminase (Aicda), activation-induced cytidine deaminase (aicda), activation-induced cytidine deaminase L homeolog (aicda.L), activation induced cytidine deaminase (aicda), AICDA, AID, Aid, aid, ARP2, Arp2, arp2, CDA2, cda2, HIGM2, higm2, xlaid

Protein level used designations for AICDA

  • cytidine aminohydrolase
  • integrated into Burkitt's lymphoma cell line Ramos
  • single-stranded DNA cytosine deaminase
  • activation induced deaminase
  • activation-induced cytidine deaminase
  • aid
  • activation induced cytidine deaminase
  • activation-induced deaminase
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