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AKAP12 Produits

(A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Catégories

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories AKAP12 en vedette

AKAP12 Anticorps

High quality antibodies with extensive validation data.

AKAP12 Kits ELISA

Reliable ELISA kits for a wide range of species.

AKAP12 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7443371
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro), FACS, IF (cc), IF (p)
Validations
  • (3)
N° du produit ABIN685732
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (2)
N° du produit ABIN564142
Quantité 100 μg
Fiche technique Fiche technique

AKAP12 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964513
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN770578
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Pig
Analytical Method Quantitative
Validations
N° du produit ABIN778155
Quantité 96 tests
Fiche technique Fiche technique

AKAP12 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1344712
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7416580
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits AKAP12

Bateman, Jaworski, Ao, Wang, Litzi, Dubil, Marcus, Conrads, Teng, Hood, Phippen, Vasicek, McGuire, Paz, Sidransky, Hamilton, Maxwell, Darcy, Conrads: "Elevated AKAP12 in paclitaxel-resistant serous ovarian cancer cells is prognostic and predictive of poor survival in patients." dans: Journal of proteome research, Vol. 14, Issue 4, pp. 1900-10, (2015) (PubMed).

Lin, Tan, Lim, Khoo, Lim, Chung: "iTRAQ analysis of colorectal cancer cell lines suggests Drebrin (DBN1) is overexpressed during liver metastasis." dans: Proteomics, Vol. 14, Issue 11, pp. 1434-43, (2014) (PubMed).

Soloff, Jeng, Izban, Sinha, Luxon, Stamnes, England: "Effects of progesterone treatment on expression of genes involved in uterine quiescence." dans: Reproductive sciences (Thousand Oaks, Calif.), Vol. 18, Issue 8, pp. 781-97, (2011) (PubMed).

Mardin, Petrov, Enns, Senninger, Haier, Mees: "SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma." dans: BMC cancer, Vol. 10, pp. 549, (2010) (PubMed).

Tan, Tan, Lin, Lim, Hew, Chung: "Quantitative and temporal proteome analysis of butyrate-treated colorectal cancer cells." dans: Molecular & cellular proteomics : MCP, Vol. 7, Issue 6, pp. 1174-85, (2008) (PubMed).

Siegel, Grove, Carr: "SSeCKS immunolabeling in rat primary sensory neurons." dans: Brain research, Vol. 926, Issue 1-2, pp. 126-36, (2002) (PubMed).

Nauert, Klauck, Langeberg, Scott: "Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein." dans: Current biology : CB, Vol. 7, Issue 1, pp. 52-62, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à AKAP12

A kinase (PRKA) anchor protein 12b (akap12b), A-kinase anchoring protein 12 (AKAP12), A kinase (PRKA) anchor protein (gravin) 12 (Akap12), A-kinase anchoring protein 12 (Akap12), AI317366, akap12, AKAP12, AKAP12A, AKAP12B, AKAP12G, AKAP250, cb27, esr1, fb72g12, id:ibd1202, sb:cb27, si:ch73-192g21.1, Srcs5, SSeCKS, Tsga12, wu:fb72g12, wu:fc21c03

Protein level used designations for AKAP12

  • A kinase (PRKA) anchor protein (gravin) 12
  • A-kinase anchor protein 12
  • gravin
  • A kinase (PRKA) anchor protein 12
  • A kinase anchor protein 12
  • A-kinase anchor protein 12-like
  • a-kinase anchor protein 12-like
  • AKAP-12
  • gercelin
  • germ cell lineage protein gercelin
  • src-suppressed C kinase substrate
  • testis specific gene A12
  • v-src suppressed transcript 5
  • SSeCKS, Gravin, AKAP250
  • A-kinase anchor protein, 250kDa
  • AKAP 250
  • Src-Suppressed C Kinase Substrate
  • kinase scaffold protein gravin
  • myasthenia gravis autoantigen gravin
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