AKAP13 Produits
(A Kinase (PRKA) Anchor Protein 13 (AKAP13))
Catégories
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012].
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Catégories AKAP13 en vedette
AKAP13 Anticorps
High quality antibodies with extensive validation data.
AKAP13 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (6)
N° du produit
ABIN524646
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (3)
N° du produit
ABIN564877
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, IF, ICC
Validations
- (3)
N° du produit
ABIN6256897
Quantité
100 μL
Fiche technique
Fiche technique
AKAP13 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648000
Quantité
96 tests
Fiche technique
Fiche technique
AKAP13 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121629
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1344715
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits AKAP13
: "The mRNA and protein expression of A-kinase anchor proteins 13 in human colorectal cancer." dans: Clinical and experimental medicine, Vol. 10, Issue 1, pp. 41-9, (2010) (PubMed).: "RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa B." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 6, pp. 3522-9, (2009) (PubMed).
: "The ubiquitin-like protein LC3 regulates the Rho-GEF activity of AKAP-Lbc." dans: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28232-42, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à AKAP13
A-kinase anchoring protein 13 (AKAP13), A-kinase anchoring protein 13 S homeolog (akap13.S), A kinase (PRKA) anchor protein 13 (akap13), A-kinase anchoring protein 13 (Akap13), A kinase (PRKA) anchor protein 13 (Akap13), 1700026G02Rik, 5730522G15Rik, 5830460E08Rik, AKAP-13, akap-lbc, AKAP-Lbc, AKAP13, arhgef13, ARHGEF13, brx, BRX, c-lbc, ha-3, HA-3, ht31, Ht31, lbc, LBC, MGC81410, p47, PRKA13, proto-lb, PROTO-LB, proto-lbc, PROTO-LBCProtein level used designations for AKAP13
- A kinase (PRKA) anchor protein 13
- A kinase anchor protein 13 isoform-like
- A-kinase anchor protein 13-like
- A-kinase anchor protein 13
- a-kinase anchor protein 13-like
- A-kinase anchoring protein
- LBC oncogene
- breast cancer nuclear receptor-binding auxiliary protein
- guanine nucleotide exchange factor Lbc
- human thyroid-anchoring protein 31
- lymphoid blast crisis oncogene
- non-oncogenic Rho GTPase-specific GTP exchange factor
- protein kinase A-anchoring protein 13
- protein kinase A anchoring protein Rt31
- type II cAMP-dependent protein kinase anchoring protein Ht31
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