ALOX5 Produits
(Arachidonate 5-Lipoxygenase (ALOX5))
Catégories
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
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Catégories ALOX5 en vedette
ALOX5 Anticorps
High quality antibodies with extensive validation data.
ALOX5 Kits ELISA
Reliable ELISA kits for a wide range of species.
ALOX5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ALOX5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7433525
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (5)
N° du produit
ABIN513267
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN3023073
Quantité
100 μL
Fiche technique
Fiche technique
ALOX5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6953906
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964998
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964995
Quantité
96 tests
Fiche technique
Fiche technique
ALOX5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1344921
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7393886
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7424545
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ALOX5
: "Modulating effect of inositol hexaphosphate on arachidonic acid-dependent pathways in colon cancer cells." dans: Prostaglandins & other lipid mediators, Vol. 131, pp. 41-48, (2018) (PubMed).: "BLT1 signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils." dans: Scientific reports, Vol. 6, pp. 29650, (2016) (PubMed).
: "Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study." dans: Atherosclerosis, Vol. 239, Issue 2, pp. 528-38, (2015) (PubMed).
: "The protective effect of caffeic acid on global cerebral ischemia-reperfusion injury in rats." dans: Behavioral and brain functions : BBF, Vol. 11, pp. 18, (2015) (PubMed).
: "Protective role of ellagitannins from Eucalyptus citriodora against ethanol-induced gastric ulcer in rats: impact on oxidative stress, inflammation and calcitonin-gene related peptide." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 22, Issue 1, pp. 5-15, (2015) (PubMed).
: "The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice." dans: Drug discoveries & therapeutics, Vol. 8, Issue 1, pp. 25-32, (2014) (PubMed).
: "5-Lipoxygenase inhibitors attenuate TNF-α-induced inflammation in human synovial fibroblasts." dans: PLoS ONE, Vol. 9, Issue 9, pp. e107890, (2014) (PubMed).
: "Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet." dans: BMC ophthalmology, Vol. 13, Issue 1, pp. 14, (2013) (PubMed).
: "Leukotriene B4 type-1 receptor signaling promotes liver repair after hepatic ischemia/reperfusion injury through the enhancement of macrophage recruitment." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 8, pp. 3132-43, (2013) (PubMed).
: "ALOX5 promoter genotype, asthma severity and LTC production by eosinophils." dans: Allergy, Vol. 61, Issue 1, pp. 97-103, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à ALOX5
arachidonate 5-lipoxygenase (ALOX5), arachidonate 5-lipoxygenase (Alox5), arachidonate 5-lipoxygenase a (alox5a), arachidonate 5-lipoxygenase (AFUA_4G02770), arachidonate 5-lipoxygenase (AOR_1_1362014), Arachidonate 5-lipoxygenase (lox5), 5-LO, 5-LOX, 5LO, 5LPG, 5LX, AI850497, F730011J02, LOG5, lox5, LOX5A, si:dkey-194n13.2Protein level used designations for ALOX5
- LOX-5
- arachidonic 5-lipoxygenase alpha-10 isoform
- arachidonic 5-lipoxygenase delta-10-13 isoform
- arachidonic 5-lipoxygenase delta-13 isoform
- arachidonic 5-lipoxygenase delta-p10 isoform
- arachidonic acid 5-lipoxygenase
- leukotriene A4 synthase
- 5-lipoxygenase
- 5 - Lipoxygenase
- 5-LO
- LOX2
- arachidonate 5-lipoxygenase
- Arachidonate 5-lipoxygenase
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