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AMACR Produits

(alpha-Methylacyl-CoA Racemase (AMACR))
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011].

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Catégories AMACR en vedette

AMACR Anticorps

High quality antibodies with extensive validation data.

AMACR Kits ELISA

Reliable ELISA kits for a wide range of species.

AMACR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

AMACR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, StM
Validations
  • (7)
N° du produit ABIN6939431
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (5)
N° du produit ABIN654069
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, StM
Validations
  • (5)
N° du produit ABIN6939430
Quantité 100 μg
Fiche technique Fiche technique

AMACR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964773
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953651
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN4993314
Quantité 96 tests
Fiche technique Fiche technique

AMACR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121802
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1344965
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7409431
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits AMACR

Drusian, Nigro, Mannella, Pagliarini, Pema, Costa, Benigni, Larcher, Chiaravalli, Gaude, Montorsi, Capitanio, Musco, Frezza, Boletta: "mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma." dans: Cell reports, Vol. 24, Issue 5, pp. 1093-1104.e6, (2018) (PubMed).

Wang, Tian, Xiao, Zhang, Sun, Tang: "A metanephric adenoma of the kidney associated with polycythemia: A case report." dans: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).

Chen, Watson, Marengo, Decker, Coleman, Nelson, Sikes: "Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo." dans: Cancer letters, Vol. 244, Issue 2, pp. 274-88, (2006) (PubMed).

Epstein, Herawi: "Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care." dans: The Journal of urology, Vol. 175, Issue 3 Pt 1, pp. 820-34, (2006) (PubMed).

Ferdinandusse, Denis, Clayton, Graham, Rees, Allen, McLean, Brown, Vreken, Waterham, Wanders: "Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy." dans: Nature genetics, Vol. 24, Issue 2, pp. 188-91, (2000) (PubMed).

Kotti, Savolainen, Helander, Yagi, Novikov, Kalkkinen, Conzelmann, Hiltunen, Schmitz: "In mouse alpha -methylacyl-CoA racemase, the same gene product is simultaneously located in mitochondria and peroxisomes." dans: The Journal of biological chemistry, Vol. 275, Issue 27, pp. 20887-95, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à AMACR

alpha-methylacyl-CoA racemase (AMACR), alpha-methylacyl-CoA racemase (mcr), PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) (mcr), alpha-methylacyl-CoA racemase (BPSL0064), Alpha-methylacyl-CoA racemase (Maqu_2037), alpha-methylacyl-CoA racemase (UREG_03852), alpha-methylacyl-CoA racemase (MCYG_01809), alpha-methylacyl-CoA racemase (amacr), alpha-methylacyl-CoA racemase L homeolog (amacr.L), alpha-methylacyl-CoA racemase (MGYG_04259), alpha-methylacyl-CoA racemase (NCU04099), alpha-methylacyl-CoA racemase (Amacr), AMACR, amacr, AMACRD, CBAS4, Da1-8, DKFZp469O1232, Macr1, Marc1, MGC89832, NCU04099.1, RACE, RM

Protein level used designations for AMACR

  • alpha-methylacyl-CoA racemase
  • Alpha-methylacyl-CoA racemase
  • alpha-methylacyl-CoA racemase-like
  • amacr protein
  • 2-methylacyl-CoA racemase
  • 2-arylpropionyl-CoA epimerase
  • alpha-methylacyl-Coenzyme A racemase
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