Anaphase Promoting Complex Subunit 11 Produits
(Anaphase Promoting Complex Subunit 11 (ANAPC11))
Catégories
Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin- conjugating E2 enzymes, it catalyzes the formation of protein- ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication. APC11 is required to recruit the ubiquitin- conjugating enzyme E2 to the APC/C.
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Catégories Anaphase Promoting Complex Subunit 11 en vedette
Anaphase Promoting Complex Subunit 11 Anticorps
High quality antibodies with extensive validation data.
Anaphase Promoting Complex Subunit 11 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Anaphase Promoting Complex Subunit 11 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IHC (p)
Validations
- (5)
N° du produit
ABIN1496631
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (4)
N° du produit
ABIN5542417
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (3)
N° du produit
ABIN565630
Quantité
100 μg
Fiche technique
Fiche technique
Anaphase Promoting Complex Subunit 11 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345030
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN2714780
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2714779
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Anaphase Promoting Complex Subunit 11
: "Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins." dans: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15758-65, (2002) (PubMed).: "Association with cullin partners protects ROC proteins from proteasome-dependent degradation." dans: Oncogene, Vol. 18, Issue 48, pp. 6758-66, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à Anaphase Promoting Complex Subunit 11
anaphase promoting complex subunit 11 (ANAPC11), anaphase promoting complex subunit 11 L homeolog (anapc11.L), anaphase promoting complex subunit 11 (anapc11), anaphase promoting complex subunit 11 (Anapc11), anaphase-promoting complex/cyclosome 11 (APC11), anaphase promoting complex subunit 11 (APC11), anaphase-promoting complex subunit Apc11 (apc11), anaphase promoting complex subunit 11 (CAALFM_CR10610CA), ubiquitin-protein ligase Anaphase Promoting Complex (APC11), hypothetical protein (APC11), predicted protein (APC11), anaphase-promoting complex subunit 11 (LOC9320604), anaphase promoting complex subunit 11 (LOC692923), APC11 anaphase promoting complex subunit 11 homolog (yeast) (anapc11), 1110011I19Rik, anapc11, anaphase-promoting complex/cyclosome 11, APC11, Apc11p, DDBDRAFT_0187183, DDBDRAFT_0231277, DDB_0187183, DDB_0231277, F10A16.17, F10A16_17, R75218, RGD1561880, si:dkey-237i9.4, zgc:153671Protein level used designations for Anaphase Promoting Complex Subunit 11
- APC11 anaphase promoting complex subunit 11 homolog
- anaphase promoting complex subunit 11 (yeast APC11 homolog)
- anaphase-promoting complex subunit 11
- cyclosome subunit 11
- hepatocellular carcinoma-associated RING finger protein
- anaphase promoting complex subunit 11
- anaphase promoting complex subunit 11 homolog
- Apc11p
- Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
- anaphase-promoting complex subunit Apc11
- potential anaphase-promoting complex subunit Apc11
- ubiquitin-protein ligase Anaphase Promoting Complex
- hypothetical protein
- anaphase-promoting complex/cyclosome 11
- APC11
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