Androgen Receptor Produits
(Androgen Receptor (AR))
Catégories
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Catégories Androgen Receptor en vedette
Androgen Receptor Anticorps
High quality antibodies with extensive validation data.
Androgen Receptor Kits ELISA
Reliable ELISA kits for a wide range of species.
Androgen Receptor Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Androgen Receptor recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (5)
- (1)
N° du produit
ABIN1871059
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
- (1)
N° du produit
ABIN2857043
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
- (5)
N° du produit
ABIN1724724
Quantité
100 μL
Fiche technique
Fiche technique
Androgen Receptor recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964823
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6974982
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953700
Quantité
96 tests
Fiche technique
Fiche technique
Androgen Receptor recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121827
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121826
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1345428
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Androgen Receptor
: "Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats." dans: Scientific reports, Vol. 8, Issue 1, pp. 490, (2018) (PubMed).: "Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer." dans: European journal of medicinal chemistry, Vol. 152, pp. 542-559, (2018) (PubMed).
: "Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer." dans: Journal of translational medicine, Vol. 16, Issue 1, pp. 356, (2018) (PubMed).
: "Effects of low dose of bisphenol A on the proliferation and mechanism of primary cultured prostate epithelial cells in rodents." dans: Oncology letters, Vol. 14, Issue 3, pp. 2635-2642, (2017) (PubMed).
: "Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 9, Issue 1, pp. 53-62, (2016) (PubMed).
: "Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 980583, (2016) (PubMed).
: "Changes in mitotic reorientation and Wnt/AR signaling in rat prostate epithelial cells exposed to subchronic testosterone." dans: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1361-1366, (2016) (PubMed).
: "Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and ..." dans: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 905-908, (2015) (PubMed).
: "Bak Foong pills combined with metformin in the treatment of a polycystic ovarian syndrome rat model." dans: Oncology letters, Vol. 10, Issue 3, pp. 1819-1825, (2015) (PubMed).
: "Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients." dans: International journal of molecular sciences, Vol. 14, Issue 8, pp. 16656-71, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à Androgen Receptor
androgen receptor (AR), androgen receptor (Ar), androgen receptor (ar), AIS, Andr, AR, AW320017, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, TfmProtein level used designations for Androgen Receptor
- androgen nuclear receptor variant 2
- dihydrotestosterone receptor
- nuclear receptor subfamily 3 group C member 4
- testicular feminization
- androgen receptor (Testicular feminization), same as Tfm
- androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
- androgen receptor AR
- AR-A
- Ar beta
- androgen receptor
- prostate androgen receptor
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