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Androgen Receptor Produits

(Androgen Receptor (AR))
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

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Catégories Androgen Receptor en vedette

Androgen Receptor Anticorps

High quality antibodies with extensive validation data.

Androgen Receptor Kits ELISA

Reliable ELISA kits for a wide range of species.

Androgen Receptor Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Androgen Receptor recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (5)
  • (1)
N° du produit ABIN1871059
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (3)
  • (1)
N° du produit ABIN2857043
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
  • (5)
N° du produit ABIN1724724
Quantité 100 μL
Fiche technique Fiche technique

Androgen Receptor recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6964823
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6974982
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6953700
Quantité 96 tests
Fiche technique Fiche technique

Androgen Receptor recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121827
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121826
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345428
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Androgen Receptor

Huang, Zheng, Pan, Wu, Su, Li, Wu, Sun: "Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats." dans: Scientific reports, Vol. 8, Issue 1, pp. 490, (2018) (PubMed).

Xue, Zhang, Wang, Zhang, Xiang, Wang, Wang, Li, Zhang, Zou, Wang, Wu, Lu, Chen, Ding, Li, Xu: "Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer." dans: European journal of medicinal chemistry, Vol. 152, pp. 542-559, (2018) (PubMed).

Pizon, Lux, Pachmann, Pachmann, Schott: "Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer." dans: Journal of translational medicine, Vol. 16, Issue 1, pp. 356, (2018) (PubMed).

Huang, Wu, Su, Yan, Sun: "Effects of low dose of bisphenol A on the proliferation and mechanism of primary cultured prostate epithelial cells in rodents." dans: Oncology letters, Vol. 14, Issue 3, pp. 2635-2642, (2017) (PubMed).

Madka, Mohammed, Li, Zhang, Biddick, Patlolla, Lightfoot, Towner, Wu, Steele, Kopelovich, Rao: "Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 9, Issue 1, pp. 53-62, (2016) (PubMed).

Zhao, Jin, Zhang, Cui, Sun, Gao, Gu, Cai: "Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 980583, (2016) (PubMed).

Liu, Cheng, Pan, Hu, Xu, Meng, Wu, Xie, Yan, Sun: "Changes in mitotic reorientation and Wnt/AR signaling in rat prostate epithelial cells exposed to subchronic testosterone." dans: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1361-1366, (2016) (PubMed).

Zhang, Shen, Cao, Yan, Ji et al.: "Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and ..." dans: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 905-908, (2015) (PubMed).

Liu, Liu, Fu, Wang, Zhang: "Bak Foong pills combined with metformin in the treatment of a polycystic ovarian syndrome rat model." dans: Oncology letters, Vol. 10, Issue 3, pp. 1819-1825, (2015) (PubMed).

McCall, Adams, Willder, Bennett, Qayyum, Orange, Underwood, Edwards: "Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients." dans: International journal of molecular sciences, Vol. 14, Issue 8, pp. 16656-71, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à Androgen Receptor

androgen receptor (AR), androgen receptor (Ar), androgen receptor (ar), AIS, Andr, AR, AW320017, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, Tfm

Protein level used designations for Androgen Receptor

  • androgen nuclear receptor variant 2
  • dihydrotestosterone receptor
  • nuclear receptor subfamily 3 group C member 4
  • testicular feminization
  • androgen receptor (Testicular feminization), same as Tfm
  • androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
  • androgen receptor AR
  • AR-A
  • Ar beta
  • androgen receptor
  • prostate androgen receptor
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