ANK2 Produits
(Ankyrin 2, Neuronal (ANK2))
Catégories
This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011].
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Catégories ANK2 en vedette
ANK2 Anticorps
High quality antibodies with extensive validation data.
ANK2 Kits ELISA
Reliable ELISA kits for a wide range of species.
ANK2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IF
Validations
- (4)
N° du produit
ABIN1027715
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IF
Validations
- (3)
N° du produit
ABIN2485091
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IF
Validations
- (3)
N° du produit
ABIN2485090
Quantité
100 μg
Fiche technique
Fiche technique
ANK2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN770590
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Pig
Analytical Method
Quantitative
Validations
N° du produit
ABIN778171
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rabbit
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN774272
Quantité
96 tests
Fiche technique
Fiche technique
ANK2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2714726
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ANK2
: "Glial ankyrins facilitate paranodal axoglial junction assembly." dans: Nature neuroscience, Vol. 17, Issue 12, pp. 1673-81, (2014) (PubMed).: "In vivo assembly of the axon initial segment in motor neurons." dans: Brain structure & function, Vol. 219, Issue 4, pp. 1433-50, (2014) (PubMed).
: "AlphaII-spectrin participates in the surface expression of cell adhesion molecule L1 and neurite outgrowth." dans: Experimental cell research, Vol. 322, Issue 2, pp. 365-80, (2014) (PubMed).
: "Proteomic analysis of gliosomes from mouse brain: identification and investigation of glial membrane proteins." dans: Journal of proteome research, Vol. 13, Issue 12, pp. 5918-27, (2014) (PubMed).
: "A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier." dans: Nature neuroscience, Vol. 17, Issue 12, pp. 1664-72, (2014) (PubMed).
: "Membrane domain organization of myelinated axons requires ?II spectrin." dans: The Journal of cell biology, Vol. 203, Issue 3, pp. 437-43, (2013) (PubMed).
: "A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly." dans: Cell, Vol. 149, Issue 5, pp. 1125-39, (2012) (PubMed).
: "Real-time CARS imaging reveals a calpain-dependent pathway for paranodal myelin retraction during high-frequency stimulation." dans: PLoS ONE, Vol. 6, Issue 3, pp. e17176, (2011) (PubMed).
: "Schwann cell spectrins modulate peripheral nerve myelination." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 19, pp. 8009-14, (2011) (PubMed).
: "Molecular microdomains in a sensory terminal, the vestibular calyx ending." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 27, pp. 10101-14, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à ANK2
ankyrin 2 (ANK2), ankyrin 2, brain (Ank2), ankyrin 2 (Ank2), ankyrin-2 (LOC539238), ankyrin 2b, neuronal (ank2b), ankyrin-2 (LOC100465763), AI835472, ANK-2, Ank-2, ANK2, ank2, Ank3, ANKB, AW491075, brank-2, CHANK2, LQT4, zgc:101738Protein level used designations for ANK2
- ankyrin B
- ankyrin, brain
- ankyrin-2
- ankyrin-2, nonerythrocytic
- non-erythroid ankyrin
- ankyrin-B
- brain ankyrin
- ankyrin 2, brain
- ankyrin 3, epithelial
- ankyrin 2, neuronal
- ankyrin-2-like
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