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NIPBL anticorps (AA 344-356)

NIPBL Reactivité: Humain ELISA, WB Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN100654
  • Antigène Voir toutes NIPBL Anticorps
    NIPBL (Nipped-B like Protein (NIPBL))
    Épitope
    • 15
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 344-356
    Reactivité
    • 16
    • 14
    • 5
    Humain
    Hôte
    • 25
    • 3
    • 1
    • 1
    Chèvre
    Clonalité
    • 26
    • 4
    Polyclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NIPBL est non-conjugé
    Application
    • 13
    • 13
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    ELISA, Western Blotting (WB)
    Attributs du produit
    Concentration Definition: by UV absorbance at 280 nm
    Stérilité
    Sterile filtered
    Immunogène
    This affinity-purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 344-356 of Human IDN3.
    Isotype
    IgG
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    Discover our top product NIPBL Anticorps primaire
  • Indications d'application
    This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect bands at 316 kDa in size corresponding to IDN3 by western blotting in the appropriate cell lysate or extract.  Splice variants for this protein may show molecular weights of 304 kDa and 122 kDa.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.6 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    NIPBL (Nipped-B like Protein (NIPBL))
    Autre désignation
    IDN3 (NIPBL Produits)
    Synonymes
    anticorps CDLS, anticorps CDLS1, anticorps IDN3, anticorps IDN3-B, anticorps Scc2, anticorps SCC2W, anticorps scc2, anticorps nipbl, anticorps scc2-2, anticorps NIPBL, anticorps nipbla, anticorps wu:fi33d08, anticorps 4921518A06Rik, anticorps 4933421G18Rik, anticorps C79399, anticorps Idn3, anticorps NIPBL, cohesin loading factor, anticorps Nipped-B homolog-like, anticorps NIPBL, cohesin loading factor S homeolog, anticorps nipped-B homolog b (Drosophila), anticorps nipped-B-like protein A, anticorps Nipped-B homolog (Drosophila), anticorps NIPBL, anticorps NIPBLL, anticorps nipbl.S, anticorps LOC427439, anticorps nipblb, anticorps LOC100164947, anticorps nipbl, anticorps Nipbl
    Sujet
    IDN3 (also known as Colon tumor susceptibility 2, DKFZp434L1319, FLJ13648, Mis 4, Scc-2, Delangin and Sister chromatid cohesion protein) is the mammalian homologue of Scc2 in S. cerevisiae and Mis4 in S. pombe. In yeast, this factor was originally identified genetically as being involved in sister chromatid cohesion; subsequent work has determined that it is not involved in cohesion directly but is required for the loading of cohesins onto chromatin during S phase. It shares 37% sequence identity with Nipped-B gene product of Drosophila, which facilitates enhancer-promoter communication of remote enhancers. The Drosophila protein is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair.  IDN3 is a nuclear protein that is widely expressed and found at the highest levels in heart, skeletal muscle, fetal and adult liver, and fetal and adult kidney. The protein is also found, albeit at lower levels of expression in thymus, placenta, peripheral leukocyte and small intestine.  Multiple isoforms of the protein have been reported.
    Synonyms: CDLS antibody, Colon tumor susceptibility 2 antibody, Delangin antibody, DKFZp434L1319 antibody, FLJ11203 antibody
    ID gène
    25836, 4760549
    UniProt
    Q6KC79
    Pathways
    Sensory Perception of Sound, Stem Cell Maintenance
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