SARS-CoV Spike anticorps (Intermediate Domain 3)

N° du produit ABIN1031207

Détail du produit anti-SARS-CoV Spike anticorps

Antigène: SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Épitope: Intermediate Domain 3

Reactivité: SARS Coronavirus (SARS-CoV)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SARS-CoV Spike est non-conjugé

Application: ELISA

Homologie: Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 40%, homology 56%)

Purification: Affinity chromatography purified via peptide column

Immunogène: Anti-SARS-CoV Spike antibody (3225) was raised against a peptide corresponding to 15 amino acids near the center of SARS-CoV Spike glycoprotein.
The immunogen is located within amino acids 650-700 of SARS-CoV Spike.

Isotype: IgG

Information d'application

Indications d'application: SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 5 ng of free peptide at 1 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: The antibody is supplied in PBS containing 0.02% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody can be stored at 4 ˚ C for three months and -20 ˚ C, stable for up to one year.

Date de péremption: 12 months

Détails sur SARS-CoV Spike

Antigène: SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Autre désignation: SARS-CoV Spike (SARS-CoV S Produits)

Classe de substances: Viral Protein

Sujet: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection. The spike protein is the major target for neutralizing antibodies and vaccine development. The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19. The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein .

ID gène: 1489668

NCBI Accession: P59594