AFAP1L1 anticorps (N-Term)

N° du produit ABIN1031218

Détail du produit anti-AFAP1L1 anticorps

Antigène: AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFAP1L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: At least four isoforms of AFAP1L1 are known to exist. This antibody is predicted to not cross-react with other AFAP family members.

Purification: Affinity chromatography purified via peptide column

Immunogène: AFAP1L1 antibody was raised against a AA 19 synthetic peptide near the amino terminus of human AFAP1L1.

Isotype: IgG

Information d'application

Indications d'application: AFAP1L1 antibody can be used for detection of AFAP1L1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Optimal dilutions for each application to be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: AFAP1L antibody can be stored at 4 °C for three months and -20 °C, stable for up to one year.

Date de péremption: 12 months

Détails sur AFAP1L1

Antigène: AFAP1L1 (Actin Filament Associated Protein 1-Like 1 (AFAP1L1))

Abstract: AFAP1L1 Produits

Sujet: Synonym:
Actin filament associated protein 1-like 1

The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation . Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas.

ID gène: 134265

NCBI Accession: NP_689619