IL-9 anticorps (Biotin)

N° du produit ABIN1043810

Détail du produit anti-IL-9 anticorps (Biotin)

Antigène: IL-9 (IL9) (Interleukin 9 (IL9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-9 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Specificité: This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-9 in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.

Attributs du produit: IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.

Purification: purified

Immunogène: This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-9 protein.
Immunogen Type: RecombinantProtein

Isotype: IgG

Information d'application

Indications d'application: This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 15 kDa in size corresponding to human IL-9 protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.

Commentaires:

Gene Name: IL9

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Date de péremption: 12 months

Références pour anticorps anti-IL-9 (Biotin) (ABIN1043810)

Zhu, Liu, Zhao, Jia, Cui, Ning: "Association analysis of polymorphisms in IL-3, IL-4, IL-5, IL-9, and IL-13 with Graves' disease." dans: Journal of endocrinological investigation, Vol. 33, Issue 10, pp. 751-5, (2010) (PubMed).

Ciprandi: "Serum interleukin 9 in allergic rhinitis." dans: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, Vol. 104, Issue 2, pp. 180-1, (2010) (PubMed).

Osterfeld, Ahrens, Strait, Finkelman, Renauld, Hogan: "Differential roles for the IL-9/IL-9 receptor alpha-chain pathway in systemic and oral antigen-induced anaphylaxis." dans: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 469-476.e2, (2010) (PubMed).

Détails sur IL-9

Antigène: IL-9 (IL9) (Interleukin 9 (IL9))

Autre désignation: IL-9 (IL9 Produits)

Synonymes: anticorps IL9, anticorps IL-9, anticorps Il-9, anticorps P40, anticorps HP40, anticorps interleukin 9, anticorps IL9, anticorps il9, anticorps Il9

Sujet: IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Synonyms: Interleukin-9, IL-9, IL9, T cell growth factor 3, T cell growth factor p40, TCGF 3, Mast cell growth factor, MCGF, Megakaryoblast growth factor, p40 cytokine

ID gène: 3578

NCBI Accession: NP_000581

UniProt: P15248

Pathways: Signalistation JAK/STAT