IDO2 anticorps

N° du produit ABIN1043821

Détail du produit anti-IDO2 anticorps

Antigène: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDO2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Anti-IDO2 was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. IDO2 antibody is specific for mouse IDO2 protein. Cross-reactivity with IDO2 from other sources has not been determined.

Attributs du produit: Indoleamine 2,3-dioxygenase 2 (IDO2) is related to IDO1, and may play a role in T and B Cell Immunity. IDO2’s role in immune regulation will be become clearer following the completion of genetic knock-out studies. IDO2 is expressed in a few select cell types and levels of protein expression appear to be very low, perhaps below the level of detection by IHC. Small-molecule inhibitors of indoleamine 2,3-dioxygenase (IDO) are currently being translated to clinic for evaluation as cancer therapeutics.

Stérilité: Sterile filtered

Immunogène: Anti-IDO2 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with complete mouse IDO2 protein followed by hybridoma development.
Immunogen Type: Recombinant Protein

Clone: 1HC

Isotype: IgG

Information d'application

Indications d'application: Anti-IDO2 antibody has been tested for use in ELISA, Western Blot, and IF. Specific conditions for reactivity should be optimized by the end user.

Commentaires:

Gene Name: Ido2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Date de péremption: 12 months

Références pour anticorps anti-IDO2 (ABIN1043821)

Wolff, Driever, Erdlenbruch, Kortmann, Rutkowski, Pietsch, Parker, Metz, Gnekow, Kramm: "Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol." dans: Cancer, Vol. 116, Issue 3, pp. 705-12, (2010) (PubMed).

Metz, Duhadaway, Rust, Munn, Muller, Mautino, Prendergast: "Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase." dans: Molecular cancer therapeutics, Vol. 9, Issue 6, pp. 1864-71, (2010) (PubMed).

Détails sur IDO2

Antigène: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Autre désignation: IDO2 (IDO2 Produits)

Synonymes: anticorps INDOL1, anticorps Indol1, anticorps AI265623, anticorps C230043N17Rik, anticorps Ido-2, anticorps indoleamine 2,3-dioxygenase 2, anticorps IDO2, anticorps Ido2

Sujet: Indoleamine 2,3-dioxygenase 2 (IDO2) is related to IDO1, and may play a role in T and B Cell Immunity. IDO2’s role in immune regulation will be become clearer following the completion of genetic knock-out studies. IDO2 is expressed in a few select cell types and levels of protein expression appear to be very low, perhaps below the level of detection by IHC. Small-molecule inhibitors of indoleamine 2,3-dioxygenase (IDO) are currently being translated to clinic for evaluation as cancer therapeutics.
Synonyms: Indoleamine 2,3-dioxygenase 2, Indol1, Indoleamine 2,3-dioxygenase-like protein 1, Indoleamine-pyrrole 2,3-dioxygenase-like protein 1, Ido-2, Ido 2, IDO2 antibody, anti-IDO2 antibody

ID gène: 209176

NCBI Accession: NP_666061

UniProt: Q8R0V5