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SPRY2 anticorps (Internal Region)

SPRY2 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1043909
  • Antigène Voir toutes SPRY2 Anticorps
    SPRY2 (Sprouty Homolog 2 (SPRY2))
    Épitope
    • 10
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 40
    • 21
    • 11
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 40
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 42
    • 3
    Polyclonal
    Conjugué
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp SPRY2 est non-conjugé
    Application
    • 37
    • 24
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Specificité
    Anti-Sprouty-2 was affinity purified from monospecific antiserum by immunoaffinity chromatography. Sprouty-2 antibody reacts with human Sprouty 2 protein. A BLAST analysis was used to suggest reactivity with Sprouty 2 from human, monkey, and orangutan based on a 100% homology with the immunizing sequence. Cross-reactivity with Sprouty2 from other sources has not been determined.
    Attributs du produit
    Sprouty was originally identified as an inhibitor of Drosophila epidermal growth factor (EGF) and fibroblast growth factor (FGF) receptor signaling during tracheal development. Four isoforms of mammalian sprouty are known (Spry1-Spry4). The role of the mammalian analogs has not been clearly elucidated although it is believed that human Sprouty-2 (hSpry2) may be an inhibitor of cellular migration and proliferation. Spry2 and Spry4 show considerable sequence homology between human and mouse at the C-terminus of the protein. Significant sequence divergence occurs at the N-terminus. Spry2 appears to be abundant in brain, lung and heart tissue, with lesser amounts found in kidney and skeletal muscle.
    Stérilité
    Sterile filtered
    Immunogène
    Anti-Sprouty-2 affinity purified antibody was purified from monospecific rabbit antiserum prepared via repeated immunizations with human sprouty-2 peptide.
    Immunogen Type: Peptide
    Isotype
    IgG
    Top Product
    Discover our top product SPRY2 Anticorps primaire
  • Indications d'application
    Anti-Sprouty-2 antibody is suitable for ELISA, IF, and western blotting. Specific conditions for reactivity should be optimized by the end user.
    Commentaires

    Gene Name: Sprouty 2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.04 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Date de péremption
    12 months
  • Zhang, Chaturvedi, Jaggar, Magnuson, Lee, Patel: "Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 3, pp. 533-8, (2005) (PubMed).

    August: "Cerebrovascular and carotid artery disease." dans: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, Vol. 92, Issue 3, pp. 253-6, (2001) (PubMed).

  • Antigène
    SPRY2 (Sprouty Homolog 2 (SPRY2))
    Autre désignation
    Sprouty-2 (SPRY2 Produits)
    Synonymes
    anticorps wu:fk66h11, anticorps wu:fk93e11, anticorps zgc:110440, anticorps hspry2, anticorps xspry2, anticorps sprouty2, anticorps Xsprouty2, anticorps sprouty-2, anticorps Xtsprouty2, anticorps hSPRY2, anticorps sprouty RTK signaling antagonist 2, anticorps sprouty RTK signaling antagonist 2 S homeolog, anticorps sprouty homolog 2 (Drosophila), anticorps spry2, anticorps SPRY2, anticorps spry2.S, anticorps Spry2
    Sujet
    Sprouty was originally identified as an inhibitor of Drosophila epidermal growth factor (EGF) and fibroblast growth factor (FGF) receptor signaling during tracheal development. Four isoforms of mammalian sprouty are known (Spry1-Spry4). The role of the mammalian analogs has not been clearly elucidated although it is believed that human Sprouty-2 (hSpry2) may be an inhibitor of cellular migration and proliferation. Spry2 and Spry4 show considerable sequence homology between human and mouse at the C-terminus of the protein. Significant sequence divergence occurs at the N-terminus. Spry2 appears to be abundant in brain, lung and heart tissue, with lesser amounts found in kidney and skeletal muscle.
    Synonyms: hSPRY 2, hSPRY2, MGC23039, Sprouty homolog 2 (Drosophila), Sprouty homolog 2, Sprouty2, Spry 2, sprouty-2, sprouty 2
    ID gène
    10253
    UniProt
    O43597
    Pathways
    EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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