LMX1B anticorps (C-Term)

N° du produit ABIN1077396

Détail du produit anti-LMX1B anticorps

Antigène: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMX1B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B.

Isotype: IgG

Information d'application

Indications d'application: LMX1B antibody can be used for detection of LMX1B by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Commentaires:

(CT) LIM homeobox transcription factor 1 beta

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: LMX1B antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur LMX1B

Antigène: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Autre désignation: LMX1B (LMX1B Produits)

Synonymes: anticorps LMX1.2, anticorps NPS1, anticorps LMX, anticorps LMX1, anticorps LMX1.1, anticorps lmx1b, anticorps lmx1b.1, anticorps Xlmx1b, anticorps lmx1b.2, anticorps LIM homeobox transcription factor 1 beta, anticorps LIM homeobox transcription factor 1, beta b, anticorps LIM homeobox transcription factor 1, beta, gene 1 S homeolog, anticorps LIM homeobox transcription factor 1, beta a, anticorps LMX1B, anticorps Lmx1b, anticorps lmx1bb, anticorps lmx1b.1.S, anticorps lmx1ba

Sujet: The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning, LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.
Synonyms: LIM homeobox transcription factor 1 beta, LIM/homeobox protein LMX1B, LIM/homeobox protein 1.2

Poids moléculaire: 45 kDa

ID gène: 4010

NCBI Accession: NP_001167617

Pathways: Dopaminergic Neurogenesis