MECR anticorps (C-Term)
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- Antigène Voir toutes MECR Anticorps
- MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MECR est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- At least two isoforms of MECR are known to exist, this antibody will detect both isoforms.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Rabbit polyclonal MECR antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MECR.
- Isotype
- IgG
- Top Product
- Discover our top product MECR Anticorps primaire
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- Indications d'application
- MECR antibody can be used for detection of MECR by Western blot at 1 - 2 μg/mL.
- Commentaires
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(CT) Mitochondrial trans-2-enoyl-CoA reductase
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- MECR antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Date de péremption
- 12 months
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- Antigène
- MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
- Autre désignation
- MECR (MECR Produits)
- Synonymes
- anticorps CGI-63, anticorps FASN2B, anticorps NRBF1, anticorps AI195831, anticorps Nrbf1, anticorps mitochondrial trans-2-enoyl-CoA reductase, anticorps MECR, anticorps Mecr
- Sujet
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The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.
Synonyms: Mitochondrial trans-2-enoyl-CoA reductase, nuclear receptor-binding factor 1, NRBF1, CGI-63, FASN2B - Poids moléculaire
- 41 kDa (calculated)
- ID gène
- 51102
- NCBI Accession
- NP_057095
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