BCL3 anticorps (C-Term)
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- Antigène Voir toutes BCL3 Anticorps
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BCL3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3.
- Isotype
- IgG
- Top Product
- Discover our top product BCL3 Anticorps primaire
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- Indications d'application
- BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL.
- Commentaires
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(CT) B-cell CLL/lymphoma 3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- BCL3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- Date de péremption
- 12 months
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- Antigène
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
- Autre désignation
- BCL3 (BCL3 Produits)
- Synonymes
- anticorps BCL3, anticorps AI528691, anticorps Bcl-3, anticorps BCL4, anticorps D19S37, anticorps B-cell CLL/lymphoma 3, anticorps B cell leukemia/lymphoma 3, anticorps BCL3, anticorps Bcl3
- Sujet
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The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-k-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-k-B proteins. The expression of this gene can be induced by NF-k-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-k-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
Synonyms: B-cell CLL/lymphoma 3, BCL-3, BCL4, D19S37, Proto-oncogene BCL3 - Poids moléculaire
- 50 kDa (calculated)
- ID gène
- 602
- NCBI Accession
- NP_005169
- Pathways
- Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus
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