SDPR anticorps (N-Term)
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- Antigène Voir toutes SDPR Anticorps
- SDPR (Serum Deprivation Response (SDPR))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SDPR est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- It is predicted to not cross-react with other members of the cavin family.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR.
- Isotype
- IgG
- Top Product
- Discover our top product SDPR Anticorps primaire
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- Indications d'application
- SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μg/mL.
- Commentaires
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(NT) Serum deprivation-response protein
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
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- Antigène
- SDPR (Serum Deprivation Response (SDPR))
- Autre désignation
- SDPR (SDPR Produits)
- Synonymes
- anticorps CAVIN2, anticorps PS-p68, anticorps SDR, anticorps cavin-2, anticorps sdr, anticorps MGC84112, anticorps sdprb, anticorps wu:fb39c08, anticorps wu:fk90b02, anticorps zgc:92231, anticorps caveolae associated protein 2, anticorps caveolae associated 2, anticorps caveolae associated protein 2 S homeolog, anticorps serum deprivation response, anticorps caveolae associated protein 2b, anticorps CAVIN2, anticorps Cavin2, anticorps cavin2.S, anticorps SDPR, anticorps cavin2b
- Sujet
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The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
Synonyms: Serum deprivation response, SDR, serum deprivation-response protein, CAVIN2, PS-p68, cavin-2, phosphatidylserine binding protein - Poids moléculaire
- 47 kDa
- ID gène
- 8436
- NCBI Accession
- NP_004648
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