PTRF anticorps (C-Term)
-
- Antigène Voir toutes PTRF Anticorps
- PTRF (Polymerase I and Transcript Release Factor (PTRF))
-
Épitope
- C-Term
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PTRF est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Specificité
- At least three isoforms of PTRF are known to exist, this antibody detects all three isoforms. It is predicted to not cross-react with other members of the cavin family.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Rabbit polyclonal PTRF antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PTRF.
- Isotype
- IgG
- Top Product
- Discover our top product PTRF Anticorps primaire
-
-
- Indications d'application
- PTRF antibody can be used for detection of PTRF by Western blot at 0.5 - 1 μg/mL.
- Commentaires
-
(CT) Polymerase I and transcript release factor
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
-
- Antigène
- PTRF (Polymerase I and Transcript Release Factor (PTRF))
- Autre désignation
- PTRF (PTRF Produits)
- Synonymes
- anticorps MGC53017, anticorps MGC89141, anticorps PTRF, anticorps fd20g07, anticorps ptrf, anticorps wu:fd20g07, anticorps zgc:162917, anticorps CAVIN, anticorps CAVIN1, anticorps CGL4, anticorps cavin-1, anticorps 2310075E07Rik, anticorps AW546441, anticorps Cav-p60, anticorps Cavin, anticorps caveolae associated protein 1 L homeolog, anticorps polymerase I and transcript release factor, anticorps caveolae associated protein 1, anticorps caveolae associated protein 1b, anticorps caveolae associated 1, anticorps cavin1.L, anticorps PTRF, anticorps cavin1, anticorps CAVIN1, anticorps cavin1b, anticorps Cavin1
- Sujet
-
The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.
Synonyms: Polymerase I and transcript release factor, FKSG13, CAVIN, CAVIN1, CGL4, cavin-1, TTF-I interacting peptide 12 - Poids moléculaire
- 43 kDa
- ID gène
- 284119
- NCBI Accession
- NP_036364
-