HNRNPL anticorps

N° du produit ABIN108588

Cité dans 9 publications. Cet anticorps anti-HNRNPL Monoclonal Souris (Clone 4D11) (ABIN108588) détecte spécifiquement HNRNPL dans WB, ELISA, IF, IHC (p), IP, FACS, ICC et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Triton.

Aperçu rapide pour HNRNPL anticorps (ABIN108588)

Antigène: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Reactivité: Humain, Souris, Rat, Triton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HNRNPL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 4D11

Détail du produit anti-HNRNPL anticorps

Purification: Protein A

Immunogène: Human hnRNP proteins (from HeLa cells) purified by affinity chromatography on ssDNA agarose

Isotype: IgG1

Information d'application

Indications d'application: Optimal antibody dilution should be determined by titration, however as a guideline try, IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.WB: 1/2000. Detects a band of approximately 64 kDa (predicted molecular weight: 64 kDa).Flow Cyt: Use 1 μg for 106 cells.

Commentaires:

Myeloma, fusion partners: SP2/0

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-HNRNPL (ABIN108588)

Peddigari, Li, Rabe, Martin: "hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition." dans: Nucleic acids research, Vol. 41, Issue 1, pp. 575-85, (2012) (PubMed).

Motta-Mena, Smith, Mallory, Jackson, Wang, Lynch: "A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs)." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 20043-53, (2011) (PubMed).

Heyd, Lynch: "Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing." dans: Molecular cell, Vol. 40, Issue 1, pp. 126-37, (2010) (PubMed).

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." dans: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Niu, Terasaki, Komatsu, Noguchi, Shichijo, Itoh: "Identification of peptides applicable as vaccines for HLA-A26-positive cancer patients." dans: Cancer science, Vol. 100, Issue 11, pp. 2167-74, (2009) (PubMed).

Jia, Liu, Tao, Kruhlak, Guo, Meyers, Baker, Zheng: "Control of the papillomavirus early-to-late switch by differentially expressed SRp20." dans: Journal of virology, Vol. 83, Issue 1, pp. 167-80, (2008) (PubMed).

Venables, Koh, Froehlich, Lapointe, Couture, Inkel, Bramard, Paquet, Watier, Durand, Lucier, Gervais-Bird, Tremblay, Prinos, Klinck, Elela, Chabot: "Multiple and specific mRNA processing targets for the major human hnRNP proteins." dans: Molecular and cellular biology, Vol. 28, Issue 19, pp. 6033-43, (2008) (PubMed).

Rothrock, House, Lynch: "HnRNP L represses exon splicing via a regulated exonic splicing silencer." dans: The EMBO journal, Vol. 24, Issue 15, pp. 2792-802, (2005) (PubMed).

Piñol-Roma, Swanson, Gall, Dreyfuss: "A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts." dans: The Journal of cell biology, Vol. 109, Issue 6 Pt 1, pp. 2575-87, (1990) (PubMed).

Détails sur HNRNPL

Antigène: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Autre désignation: hnRNP L

Sujet: Synonyms:
D830027H13Rik antibody,FLJ35509 antibody,Heterogeneous nuclear ribonucleoprotein L antibody,hnRNPLantibody,hnRPL antibody,P/OKcl.14 antibody

ID gène: 3191, 15388, 80846

OMIM: 603083

UniProt: P31943