HNRNPL anticorps

N° du produit ABIN108588

Détail du produit anti-HNRNPL anticorps

Antigène: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Reactivité: Humain, Souris, Rat, Triton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HNRNPL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Protein A

Immunogène: Human hnRNP proteins (from HeLa cells) purified by affinity chromatography on ssDNA agarose

Clone: 4D11

Isotype: IgG1

Information d'application

Indications d'application: Optimal antibody dilution should be determined by titration, however as a guideline try, IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.WB: 1/2000. Detects a band of approximately 64 kDa (predicted molecular weight: 64 kDa).Flow Cyt: Use 1 μg for 106 cells.

Commentaires:

Myeloma, fusion partners: SP2/0

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-HNRNPL (ABIN108588)

Peddigari, Li, Rabe, Martin: "hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition." dans: Nucleic acids research, Vol. 41, Issue 1, pp. 575-85, (2012) (PubMed).

Motta-Mena, Smith, Mallory, Jackson, Wang, Lynch: "A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs)." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 20043-53, (2011) (PubMed).

Heyd, Lynch: "Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing." dans: Molecular cell, Vol. 40, Issue 1, pp. 126-37, (2010) (PubMed).

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." dans: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Niu, Terasaki, Komatsu, Noguchi, Shichijo, Itoh: "Identification of peptides applicable as vaccines for HLA-A26-positive cancer patients." dans: Cancer science, Vol. 100, Issue 11, pp. 2167-74, (2009) (PubMed).

Jia, Liu, Tao, Kruhlak, Guo, Meyers, Baker, Zheng: "Control of the papillomavirus early-to-late switch by differentially expressed SRp20." dans: Journal of virology, Vol. 83, Issue 1, pp. 167-80, (2008) (PubMed).

Venables, Koh, Froehlich, Lapointe, Couture, Inkel, Bramard, Paquet, Watier, Durand, Lucier, Gervais-Bird, Tremblay, Prinos, Klinck, Elela, Chabot: "Multiple and specific mRNA processing targets for the major human hnRNP proteins." dans: Molecular and cellular biology, Vol. 28, Issue 19, pp. 6033-43, (2008) (PubMed).

Rothrock, House, Lynch: "HnRNP L represses exon splicing via a regulated exonic splicing silencer." dans: The EMBO journal, Vol. 24, Issue 15, pp. 2792-802, (2005) (PubMed).

Piñol-Roma, Swanson, Gall, Dreyfuss: "A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts." dans: The Journal of cell biology, Vol. 109, Issue 6 Pt 1, pp. 2575-87, (1990) (PubMed).

Détails sur HNRNPL

Antigène: HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Autre désignation: hnRNP L (HNRNPL Produits)

Synonymes: anticorps HNRPL, anticorps hnRNP-L, anticorps zgc:55429, anticorps HNRNPL, anticorps hnrpl, anticorps C79783, anticorps D830027H13Rik, anticorps Hnrpl, anticorps hnrnp-L, anticorps heterogeneous nuclear ribonucleoprotein L, anticorps HNRNPL, anticorps hnrpl, anticorps hnrnpl, anticorps Hnrnpl

Sujet: Synonyms:
D830027H13Rik antibody,FLJ35509 antibody,Heterogeneous nuclear ribonucleoprotein L antibody,hnRNPLantibody,hnRPL antibody,P/OKcl.14 antibody

ID gène: 3191, 15388, 80846

OMIM: 603083

UniProt: P31943