Transportin 1 anticorps

N° du produit ABIN108619

Détail du produit anti-Transportin 1 anticorps

Antigène: Transportin 1 (TNPO1)

Reactivité: Humain, Souris, Singe, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transportin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: Protein A

Immunogène: Recombinant his tagged transportin1 (Human)

Clone: D45

Isotype: IgG1

Information d'application

Indications d'application: Optimal antibody dilution should be determined by titration, however as a guideline try,Flow Cyt: Use 1 μg for 106 cells.ICC/IF: Use a concentration of 5 μg/mL.IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.WB: 1:800. Detects a band of approximately 93 kDa (predicted molecular weight: 107 kDa)

Commentaires:

Myeloma, fusion partners: SP2/0

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Transportin 1 (ABIN108619)

Yu, Boyce, Wands, Bond, Bertozzi, Kohler: "Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 13, pp. 4834-9, (2012) (PubMed).

Brelstaff, Lashley, Holton, Lees, Rossor, Bandopadhyay, Revesz: "Transportin1: a marker of FTLD-FUS." dans: Acta neuropathologica, Vol. 122, Issue 5, pp. 591-600, (2011) (PubMed).

Gu, Tsuji, Jarboui, Yeo, Sheehy, Hall, Gautier: "Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import." dans: Retrovirology, Vol. 8, pp. 17, (2011) (PubMed).

Chen, Shao, Cobos, Wang, Gao: "4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone [corrected] induces CRM1-dependent p53 nuclear accumulation in human bronchial epithelial cells." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 116, Issue 1, pp. 206-15, (2010) (PubMed).

Janiszewska, De Vito, Le Bitoux, Fusco, Stamenkovic: "Transportin regulates nuclear import of CD44." dans: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30548-57, (2010) (PubMed).

Favre, Camps, Arod, Chabert, Rommel, Pasquali: "Chemokine receptor CCR2 undergoes transportin1-dependent nuclear translocation." dans: Proteomics, Vol. 8, Issue 21, pp. 4560-76, (2008) (PubMed).

Détails sur Transportin 1

Antigène: Transportin 1 (TNPO1)

Autre désignation: Transportin 1  (TNPO1 Produits)

Sujet: Synonyms:
Importin beta 2 antibody,IPO 2 antibody,IPO2 antibody,Karyopherin (importin) beta 2antibody,Karyopherin beta 2 antibody,KPN B2 antibody,KPNB 2 antibody,KPNB2 antibody,M9 interacting proteinantibody,M9 region interacting protein antibody,M9 region interaction protein antibody,M9-interacting proteinantibody,MIP 1 antibody,MIP antibody,MIP1 antibody,TNPO 1 antibody,TNPO1 antibody,Transportinantibody,Transportin-1 antibody,Transportin1 antibody,TRN antibody

OMIM: 602901

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events