IL13RA2 anticorps (Extracellular Domain)

N° du produit ABIN108717

Détail du produit anti-IL13RA2 anticorps

Antigène: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Épitope: Extracellular Domain

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL13RA2 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Cell-ELISA (cELISA)

Specificité: GM1C8 recognises IL-13Ralpha1 transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes (Myrtek et al., 2004).

Purification: Protein G

Immunogène: genetic immunisation with cDNA encoding human IL13-Ralpha1 (extracellular domain)

Clone: GM-1C8

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C

Stockage commentaire: short term: 2 °C - 8 °C, long term: -20 °C

Détails sur IL13RA2

Antigène: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Autre désignation: IL13R (IL13RA2 Produits)

Synonymes: anticorps il-13ra2, anticorps sb:cb602, anticorps si:dkeyp-110c7.6, anticorps CD213A2, anticorps CT19, anticorps IL-13R, anticorps IL13BP, anticorps CD213a2, anticorps IL-13R-alpha-2, anticorps IL13RA2, anticorps interleukin 13 receptor, alpha 2, anticorps interleukin 13 receptor subunit alpha 2, anticorps interleukin 13 receptor subunit alpha 2 S homeolog, anticorps il13ra2, anticorps IL13RA2, anticorps il13ra2.S, anticorps Il13ra2

Sujet: Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Rα1 together with IL-4Rα forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation.

UniProt: P78552