RAG1 anticorps (AA 818-868)

N° du produit ABIN1098121

Détail du produit anti-RAG1 anticorps

Antigène: RAG1 (Recombination Activating Gene 1 (RAG1))

Épitope: AA 818-868

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAG1 est non-conjugé

Application: ELISA

Fonction: RAG1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human RAG1 (AA: 818-868) expressed in E. Coli.

Clone: 1D9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-RAG1 (ABIN1098121)

Chen, Xiao, Zhang, Li, Liu, Zhao, Ma, Luo, Qiu, Huang, Korteweg, Gu: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." dans: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).

Jones, Bhattacharyya, Simkus, Vallieres, Veenstra, Zhou: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." dans: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).

Détails sur RAG1

Antigène: RAG1 (Recombination Activating Gene 1 (RAG1))

Autre désignation: RAG1 (RAG1 Produits)

Synonymes: anticorps RAG-1, anticorps rag1, anticorps RNF74, anticorps Rag-1, anticorps rag-1, anticorps rag1a, anticorps recombination activating 1, anticorps recombination activating gene 1, anticorps recombination activating gene 1 S homeolog, anticorps Rag1, anticorps RAG1, anticorps rag1, anticorps rag1.S

Sujet:

Description: The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.

Aliases: RAG-1, RNF74, MGC43321

Poids moléculaire: 119kDa

ID gène: 5896

HGNC: 5896

UniProt: P15918