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NEFH anticorps (AA 968-1020)

Name: NEFH anticorps (AA 968-1020)
Brand: antibodies-online
SKU: ABIN1098127
Price: 614.71 EUR
Availability: InStock

NEFH Reactivité: Humain IHC, ELISA Hôte: Souris Monoclonal 8H10 unconjugated

Immunohistochemical analysis of paraffin-embedded medulla oblongata tissues using NEFH mouse mAb with DAB staining. (NEFH anticorps (AA 968-1020))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (NEFH anticorps (AA 968-1020))

ELISA

Western blot analysis using NEFH mAb against human NEFH recombinant protein. (NEFH anticorps (AA 968-1020))

Western blot analysis using NEFH mAb against HEK293 (1) and NEFH (AA: 968-1020)-hIgGFc transfected HEK293 (2) cell lysate. (NEFH anticorps (AA 968-1020))

4 images

(2 références)

N° du produit ABIN1098127

Fiche de données

Antigène Voir toutes NEFH Anticorps

NEFH (Neurofilament, Heavy Polypeptide (NEFH))
Épitope
16

8

4

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 968-1020
Reactivité
111

82

63

49

30

23

12

12

9

9

9

7

7

5

3

3

2

1

1

1
Humain
Hôte
66

56

8
Souris
Anticorps secondaires appropriés
Clonalité
80

50
Monoclonal
Conjugué
81

5

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp NEFH est non-conjugé
Application
81

38

37

25

25

23

18

14

13

13

12

9

5

2

2

2

2

2

1

1

1
Immunohistochemistry (IHC), ELISA

Fonction

NEFH Antibody

Purification

Purified antibody

Immunogène

Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.

Clone

8H10

Isotype

IgG1

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anti-Neurofilament, Heavy Polypeptide (NEFH) antibody
NEFH Reactivité: Humain, Rat, Souris, Poulet, Porc WB, IHC, FACS, StM Hôte: Lapin Monoclonal NEFL-H-2324R unconjugated Recombinant Antibody

Indications d'application

ELISA: 1/10000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." dans: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).

Sellner, Patel, Dassan, Brown, Petzold: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." dans: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).
Antigène

NEFH (Neurofilament, Heavy Polypeptide (NEFH))

Autre désignation

NEFH (NEFH Produits)

Synonymes

anticorps NF-H, anticorps NF200, anticorps Nfh, anticorps mKIAA0845, anticorps NFH, anticorps NEFH, anticorps neurofilament heavy polypeptide, anticorps neurofilament, heavy polypeptide, anticorps neurofilament heavy, anticorps MCYG_06231, anticorps Nefh, anticorps NEFH

Sujet

Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Aliases: NFH

Poids moléculaire

112.4kDa

ID gène

4744

HGNC

4744

UniProt

P12036