Surfactant Protein C anticorps (AA 60-180)

N° du produit ABIN1098147

Détail du produit anti-Surfactant Protein C anticorps

Antigène: Surfactant Protein C (SFTPC)

Épitope: AA 60-180

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Surfactant Protein C est non-conjugé

Application: ELISA

Fonction: SFTPC Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SFTPC (AA: 60-180 ) expressed in E. Coli.

Clone: 5E6A9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Surfactant Protein C (ABIN1098147)

Zhong, Zhou, Ann, Minoo, Liu, Banfalvi, Krishnaveni, Dubourd, Demaio, Willis, Kim, duBois, Crandall, Beers, Borok: "Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein." dans: American journal of respiratory cell and molecular biology, Vol. 45, Issue 3, pp. 498-509, (2011) (PubMed).

Wang, Bridges, Na, Xu, Weaver: "Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C." dans: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33377-83, (2009) (PubMed).

Détails sur Surfactant Protein C

Antigène: Surfactant Protein C (SFTPC)

Autre désignation: SFTPC (SFTPC Produits)

Synonymes: anticorps SFTPC, anticorps SPC, anticorps SP-C, anticorps psp-c, anticorps sftp2, anticorps xSP-C, anticorps Bricd6, anticorps SP5, anticorps Sftp-2, anticorps Sftp2, anticorps pro-SpC, anticorps BRICD6, anticorps PSP-C, anticorps SFTP2, anticorps SMDP2, anticorps surfactant protein C, anticorps surfactant, pulmonary-associated protein C S homeolog, anticorps surfactant, pulmonary-associated protein C, anticorps surfactant associated protein C, anticorps SFTPC, anticorps sftpc.S, anticorps sftpc, anticorps Sftpc

Sujet:

Description: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Aliases: SP-C, PSP-C, SFTP2, SMDP2

Poids moléculaire: 21kDa

ID gène: 6440

HGNC: 6440

UniProt: P11686