Mesp2 anticorps (AA 37-94)

N° du produit ABIN1098148

Détail du produit anti-Mesp2 anticorps

Antigène: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Épitope: AA 37-94

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Mesp2 est non-conjugé

Application: ELISA

Fonction: MESP2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human MESP2 (AA: 37-94 ) expressed in E. Coli.

Clone: 1B3F9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Mesp2 (ABIN1098148)

Qiu, Zhou, Jiang, Ji, Ding, Lv, Liu, Tang, Cheng, Qiu: "Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis." dans: Studies in health technology and informatics, Vol. 176, pp. 52-5, (2012) (PubMed).

Cornier, Staehling-Hampton, Delventhal, Saga, Caubet, Sasaki, Ellard, Young, Ramirez, Carlo, Torres, Emans, Turnpenny, Pourquié: "Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome." dans: American journal of human genetics, Vol. 82, Issue 6, pp. 1334-41, (2008) (PubMed).

Détails sur Mesp2

Antigène: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Autre désignation: MESP2 (Mesp2 Produits)

Synonymes: anticorps bHLHc6, anticorps SCDO2, anticorps mesoderm posterior 2, anticorps mesoderm posterior bHLH transcription factor 2, anticorps Mesp2, anticorps MESP2

Sujet:

Description: This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Aliases: SCDO2, bHLHc6

Poids moléculaire: 41.8kDa

ID gène: 145873

HGNC: 145873

UniProt: Q0VG99