Osteopontin anticorps (AA 167-314)

N° du produit ABIN1098149

Détail du produit anti-Osteopontin anticorps

Antigène: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Épitope: AA 167-314

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Osteopontin est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Fonction: SPP1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. Coli.

Clone: 7C5H12

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Osteopontin (ABIN1098149)

Liersch, Gerss, Schliemann, Bayer, Schwöppe, Biermann, Appelmann, Kessler, Löwenberg, Büchner, Hiddemann, Müller-Tidow, Berdel, Mesters: "Osteopontin is a prognostic factor for survival of acute myeloid leukemia patients." dans: Blood, Vol. 119, Issue 22, pp. 5215-20, (2012) (PubMed).

Wang, Wang, Tang: "Osteopontin expression in nasopharyngeal carcinoma: its relevance to the clinical stage of the disease." dans: Journal of cancer research and therapeutics, Vol. 7, Issue 2, pp. 138-42, (2011) (PubMed).

Détails sur Osteopontin

Antigène: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Autre désignation: SPP1 (SPP1 Produits)

Synonymes: anticorps BNSP, anticorps BSPI, anticorps ETA-1, anticorps OPN, anticorps 2AR, anticorps Apl-1, anticorps Bsp, anticorps Eta, anticorps OP, anticorps Opn, anticorps Opnl, anticorps Ric, anticorps Spp-1, anticorps OSP, anticorps zgc:111821, anticorps secreted phosphoprotein 1, anticorps SPP1, anticorps Spp1, anticorps spp1

Sujet:

Description: The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

Aliases: OPN, BNSP, BSPI, ETA-1

Poids moléculaire: 35.4kDa

ID gène: 6696

HGNC: 6696

UniProt: P10451

Pathways: Regulation of Cell Size