ABAT anticorps (Middle Region)
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- Antigène Voir toutes ABAT Anticorps
- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Porc, Xenopus laevis
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ABAT est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- IIVEPIQSEG GDNHASDDFF RKLRDIARKH GCAFLVDEVQ TGGGCTGKFW
- Réactivité croisée (Details)
- Species reactivity (expected):Mouse, Rat, Pig, African clawed frog, Bovine, Zebrafish, Horse, Chicken, Dog, GoatSpecies reactivity (tested):Human.
- Purification
- Immunoaffinity column
- Immunogène
- Synthetic peptide directed towards the middle region of human ABAT
- Top Product
- Discover our top product ABAT Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- Antigène
- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
- Autre désignation
- ABAT (ABAT Produits)
- Synonymes
- anticorps cb880, anticorps fj82a01, anticorps wu:fj82a01, anticorps BA0325, anticorps PSPTO0259, anticorps PSPTO0301, anticorps PSPTO1890, anticorps GABA-AT, anticorps GABAT, anticorps NPD009, anticorps GABA-T, anticorps L-AIBAT, anticorps 9630038C02Rik, anticorps AI255750, anticorps ENSMUSG00000051226, anticorps Gabaat, anticorps Gabat, anticorps Gm9851, anticorps I54, anticorps Laibat, anticorps X61497, anticorps beta-AlaAT, anticorps 4-aminobutyrate aminotransferase, anticorps 4-aminobutyrate--2-oxoglutarate transaminase, anticorps GABA aminotransferase PLP-dependent PuuE, anticorps 4-aminobutyrate aminotransferase, mitochondrial, anticorps aspartate aminotransferase family protein, anticorps 4-aminobutyrate aminotransferase S homeolog, anticorps ABAT, anticorps abat, anticorps gabT, anticorps puuE, anticorps gabT-1, anticorps gabT-2, anticorps gabT-3, anticorps CNE01830, anticorps Mmwyl1_0047, anticorps CpipJ_CPIJ008729, anticorps KCR_RS04555, anticorps Bcenmc03_4909, anticorps Hden_0972, anticorps Dbac_2000, anticorps Mesil_2400, anticorps Trad_0121, anticorps abat.S, anticorps Abat
- Sujet
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.Synonyms: 4-aminobutyrate aminotransferase, GABA aminotransferase, GABAT, Gamma-amino-N-butyrate transaminase, L-AIBAT
- ID gène
- 18
- NCBI Accession
- NP_065737
- Pathways
- Monocarboxylic Acid Catabolic Process
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