AMD1 anticorps (C-Term)

N° du produit ABIN1105345

Détail du produit anti-AMD1 anticorps

Antigène: AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody detects AMD1 (C-term). No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogène: Synthetic peptide corresponding to a sequence at the C-terminal of human SAMDC .Remarks: Sequence is identical to the related mouse and rat sequence.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur AMD1

Antigène: AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

Autre désignation: AMD1 (AMD1 Produits)

Synonymes: anticorps ADOMETDC, anticorps AMD, anticorps SAMDC, anticorps Amd1a, anticorps Amd1b, anticorps AMD1, anticorps AdoMetDC, anticorps amd, anticorps samdc, anticorps fb26e03, anticorps si:ch211-257g8.2, anticorps wu:fb26e03, anticorps zgc:55614, anticorps 1, anticorps Amd-1, anticorps SAMDC 1, anticorps adoMetDC1, anticorps CG5029, anticorps Dmel\\CG5029, anticorps l(2)31Dc, anticorps l(2)31Dd, anticorps l(2)31De, anticorps F16B3.10, anticorps F16B3_10, anticorps S-ADENOSYLMETHIONINE DECARBOXYLASE, anticorps S-adenosylmethionine decarboxylase, anticorps adenosylmethionine decarboxylase 1, anticorps S-adenosylmethionine decarboxylase 1, anticorps S-adenosyl methionine decarboxylase 2, anticorps adenosylmethionine decarboxylase 1 L homeolog, anticorps S-adenosylmethionine decarboxylase, anticorps AMD1, anticorps Amd1, anticorps amd1, anticorps sam2, anticorps amd1.L, anticorps SamDC, anticorps SAMDC

Sujet: S-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC), is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.Synonyms: AdoMetDC, S-adenosylmethionine decarboxylase proenzyme, SAMDC

ID gène: 262

NCBI Accession: NP_001625

UniProt: P17707

Pathways: Ribonucleoside Biosynthetic Process