CDH23 anticorps (N-Term)

N° du produit ABIN1105632

Détail du produit anti-CDH23 anticorps

Antigène: CDH23 (Cadherin 23 (CDH23))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDH23 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of total CDH23 protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide from Human CDH23. Epitope: N-Terminus

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 50 % Glycerol, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CDH23

Antigène: CDH23 (Cadherin 23 (CDH23))

Autre désignation: Cadherin-23 (CDH23 Produits)

Synonymes: anticorps 4930542A03Rik, anticorps USH1D, anticorps ahl, anticorps ahl1, anticorps bob, anticorps bus, anticorps mdfw, anticorps nmf112, anticorps nmf181, anticorps nmf252, anticorps sals, anticorps v, anticorps CDHR23, anticorps W, anticorps cadherin 23 (otocadherin), anticorps cadherin related 23, anticorps cadherin-related 23, anticorps Cdh23, anticorps CDH23

Sujet: Cadherin like 23 (or Cadherin 23) is, like other members of the cadherin family, a calcium-dependent cell adhesion glycoprotein that preferentially interacts with itself in connecting cells. It is a single pass type I membrane protein that contains 27 cadherin domains. Cadherin like 23 is expressed in the neurosensory epithelium, where it is thought to be involved in stereocilia organisation and hair bundle formation. Defects in the gene encoding Cadherin like 23 are a cause of Usher syndrome, which is characterised by profound congenital sensorineural deafness and eventual blindness. Mutations in this gene are also a cause of non-syndromic sensorineural deafness autosomal recessive type 12 (DFNB12). Cadherin like 23 has also been associated with age-related hearing loss.Synonyms: CDH23, KIAA1774, KIAA1812

ID gène: 64072

NCBI Accession: NP_001165401

Pathways: Sensory Perception of Sound