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Caspase 2 anticorps (C-Term)
CASP2
Reactivité: Humain, Souris, Rat
WB, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN1105674
Détail du produit anti-Caspase 2 anticorps
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Antigène
Voir toutes Caspase 2 (CASP2) Anticorps
Caspase 2 (CASP2)
(Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
Épitope
Tous les épitopes à travers Caspase 2 Anticorps.
C-Term
Reactivité
Toutes les réactivités sur Caspase 2 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur Caspase 2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur Caspase 2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Caspase 2 Anticorps
Cet anticorp Caspase 2 est non-conjugé
Application
Tous les applications à travers Caspase 2 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
This antibody detects Caspase-2 (C-term). No cross reactivity with other proteins.
Réactivité croisée (Details)
Species reactivity (expected):Mouse. Species reactivity (tested):Human, Rat.
Purification
Immunoaffinity Chromatography
Immunogène
Synthetic peptide mapping at the C-terminal of Human Caspase 2 .Remarks: Sequence is identical to the related Rat and Mouse sequence.
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Reconstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur Caspase 2
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Antigène
Caspase 2 (CASP2)
(Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
Autre désignation
Caspase-2 (CASP2 Produits )
Synonymes
anticorps xCaspase-2, anticorps Caspase-2, anticorps ICH-1, anticorps Nedd2, anticorps CASP-2, anticorps ICH1, anticorps NEDD-2, anticorps NEDD2, anticorps PPP1R57, anticorps ICH-1L/1S, anticorps ICH1L1S, anticorps caspase 2, anticorps caspase 2 L homeolog, anticorps caspase-2, anticorps CASP2, anticorps casp2.L, anticorps CpipJ_CPIJ008254, anticorps Casp2
Sujet
Caspase-2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. activation of caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli. Caspase-2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2
ID gène
835
NCBI Accession
NP_116764
UniProt
P42575
Pathways
Apoptose , Caspase Cascade in Apoptosis , Neurotrophin Signaling Pathway
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