×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
CD130/gp130 anticorps
IL6ST
Reactivité: Humain
FACS, Func
Hôte: Souris
Monoclonal
B-R3
unconjugated
N° du produit ABIN1105850
Détail du produit anti-CD130/gp130 anticorps
(cache)
Antigène
Voir toutes CD130/gp130 (IL6ST) Anticorps
CD130/gp130 (IL6ST)
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
Reactivité
Toutes les réactivités sur CD130/gp130 Anticorps
Humain
Hôte
Toutes les hôtes sur CD130/gp130 Anticorps
Souris
Clonalité
Toutes les clonalités sur CD130/gp130 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CD130/gp130 Anticorps
Cet anticorp CD130/gp130 est non-conjugé
Application
Tous les applications à travers CD130/gp130 Anticorps.
Flow Cytometry (FACS), Functional Studies (Func)
Specificité
Recognises the soluble antigen. Recognises the Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein.
Réactivité croisée (Details)
Species reactivity (tested):Human.
Purification
Ion Exchange Chromatography
Stérilité
0.22 μm filtered
Immunogène
Natural soluble gp130.
Clone
B-R3
Isotype
IgG2a
Top Product
Discover our top product IL6ST Anticorps primaire
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
(cache)
Concentration
1.0 mg/mL
Buffer
PBS, Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free
Agent conservateur
Without preservative
Stock
4 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C.
Détails sur CD130/gp130
(cache)
Antigène
CD130/gp130 (IL6ST)
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
Autre désignation
CD130 / IL6ST (IL6ST Produits )
Synonymes
anticorps CD130, anticorps CDW130, anticorps GP130, anticorps IL-6RB, anticorps 5133400A03Rik, anticorps AA389424, anticorps BB405851, anticorps D13Ertd699e, anticorps gp130, anticorps Ac1055, anticorps Gp130, anticorps Il-6rb, anticorps IL-6, anticorps interleukin 6 signal transducer, anticorps IL6ST, anticorps Il6st, anticorps il6st
Sujet
CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: IL-6R-beta, IL6 receptor beta, Interleukin-6 receptor subunit beta
ID gène
3572
NCBI Accession
NP_002175
UniProt
P40189
Pathways
Signalistation JAK/STAT , Cellular Glucan Metabolic Process , Autophagy , Smooth Muscle Cell Migration , Cancer Immune Checkpoints
Vus récemment
(cache)