TLR1 anticorps (FITC)
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- Antigène Voir toutes TLR1 Anticorps
- TLR1 (Toll-Like Receptor 1 (TLR1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TLR1 est conjugé à/à la FITC
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Protein G
- Immunogène
- TLR1Fc
- Clone
- GD2-F4
- Isotype
- IgG1
- Top Product
- Discover our top product TLR1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, 1 % bovine serum albumin
- Stock
- 4 °C
- Stockage commentaire
- Store at 2 - 8 °C.
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- Antigène
- TLR1 (Toll-Like Receptor 1 (TLR1))
- Autre désignation
- CD281 / TLR1 (TLR1 Produits)
- Synonymes
- anticorps CD281, anticorps TIL, anticorps TIL. LPRS5, anticorps rsc786, anticorps toll like receptor 1, anticorps toll-like receptor 1, anticorps TLR1, anticorps Tlr1
- Sujet
- Toll-like receptors (TLR) are highly conserved throughout evolution and play an essential role in recognizing conserved motifs found in various pathogens and initiating an appropriate innate immune response. In human, ten members of the TLR family have been identified as type I transmembrane signaling receptors containing multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Mammalian responsiveness to microbial products may be mediated by combinations of TLRs, for example a co-operative effect is observed between TLR1 and TLR2 in response to bacterial lipoproteins. On the other hand, TLR 1 was shown to have the capacity to abrogate TLR4 signaling. In general, TLR1 is expressed at higher levels as compared to other TLRs. The highest expression of TLR1 is found in monocytes but it can also be expressed by macrophages, dendritic cells, B, T, and NK cells. In recent studies, several human TLR1 polymorphisms have been associated with impaired mycobacterial signaling and susceptibility to tuberculosis.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein
- ID gène
- 9606
- UniProt
- Q15399
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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